About: A controlled trial on the effect of feeding dietary chestnut extract and glycerol monolaurate on liver function in newborn calves

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: A controlled trial on the effect of feeding dietary chestnut extract and glycerol monolaurate on liver function in newborn calves Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	A controlled trial on the effect of feeding dietary chestnut extract and glycerol monolaurate on liver function in newborn calves
Creator	Knubben-Schweizer, G Bauer, J Weber, B Sauter-Louis, C Hafner-Marx, A Metzner, M Wieland, M
source	Medline; PMC
abstract	Beginning in the fall of 2010, an increasing and alarming number of cases of calves suffering from liver dystrophy were reported in the south of Germany. An epidemiological investigation was carried out by the authors between November 2010 and July 2011, leading to the implication of a commercial dietary supplement as the potential cause for this outbreak. The components of this product were first tested in a cell culture model and two of them (dietary chestnut extract and glycerol monolaurate) showed a cytotoxic effect. The objective of this study was therefore to evaluate the effect of supplemental feeding of both components alone or in combination on liver function in newborn calves on a commercial dairy farm. Ten calves were enrolled in each of the three treatment groups and the control group (group O) following a blocked design. Treatment consisted of supplementation with chestnut extract at 0.02% of birth body mass (BM) (group C), supplementation with glycerol monolaurate at 0.006% of BM (group G) or a combined treatment (group CG) for five consecutive days. The effect of treatments on liver function was evaluated clinically and by measurement of glutamate dehydrogenase (GLDH) and aspartate aminotransferase (AST) activities as well as the determination of the concentrations of glucose, L‐lactate and total bilirubin in serum. There was a significant increase in GLDH and AST activities and a significant decrease in glucose concentration in treatment groups C and CG compared with the control group (p ≤ 0.035), whereas no difference was shown for group G. Survival was significantly decreased in groups C (p = 0.029) and CG (p = 0.001) compared with both group G and the control group. These results suggest that dietary chestnut extract in an amount of 0.02% of BM alone or in combination has a toxic effect on liver function in newborn calves.
has issue date	2014-03-10(xsd:dateTime)
bibo:doi	10.1111/jpn.12179
bibo:pmid	24605953
has license	no-cc
sha1sum (hex)	bacb90870fa579e5d06df17e97d164bfd1927a4f
schema:url	https://doi.org/10.1111/jpn.12179
resource representing a document's title	A controlled trial on the effect of feeding dietary chestnut extract and glycerol monolaurate on liver function in newborn calves
has PubMed Central identifier	PMC7167178
has PubMed identifier	24605953
schema:publication	J Anim Physiol Anim Nutr (Berl)
resource representing a document's body	covid:bacb90870fa579e5d06df17e97d164bfd1927a4f#body_text
is schema:about of	named entity 'mass' named entity 'AST' named entity 'evaluate' named entity 'glutamate dehydrogenase' named entity 'activities' named entity 'determination' named entity 'activities' named entity 'calves' named entity 'controlled' named entity '0.035' named entity 'CALVES' named entity 'INCREASE' named entity 'MEASUREMENT' named entity 'COMPONENTS' named entity 'JULY' named entity 'OBJECTIVE' named entity 'BLOCKED' named entity 'TESTED' named entity 'SUPPLEMENTATION' named entity 'SUFFERING' named entity 'FOLLOWING' named entity 'tested' named entity 'measurement' named entity 'Germany' named entity 'serum' named entity 'group G' named entity 'body' named entity 'south' named entity 'suffering' named entity 'cytotoxic' named entity 'design' named entity 'group G' named entity 'calves' named entity 'extract' named entity 'total bilirubin' named entity 'dietary supplement' named entity 'glucose' named entity 'control group' named entity 'serum' named entity 'treatment groups' named entity 'treatment groups' named entity 'monolaurate' named entity 'newborn calves' named entity 'dehydration' named entity 'hepatic failure' named entity 'caecal' named entity 'chestnut' named entity 'tannins' named entity 'monogastric' named entity 'glycerol' named entity 'Armonk' named entity 'IV fluids' named entity 'SPSS' named entity 'salt' named entity 'body mass' named entity 'MTT assay' named entity 'L-lactate' named entity 'glycerol' named entity 'L-lactate' named entity 'glucose' named entity 'marbofloxacin' named entity 'sympathetic activity' named entity 'histopathologically' named entity 'Animal Physiology' named entity 'Statistically significant' named entity 'pneumonia' named entity 'necrosis' named entity 'Traunstein' named entity 'septicaemia' named entity 'liver disease' named entity 'AST' named entity 'L-lactate' named entity 'Upper Bavaria' named entity 'reference range' named entity 'neonatal'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software