About: Quality assessment and response to less invasive surfactant administration (LISA) without sedation

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About: Quality assessment and response to less invasive surfactant administration (LISA) without sedation Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Quality assessment and response to less invasive surfactant administration (LISA) without sedation
Creator	Andriessen, Peter De Kort, Ellen Kusters, Suzanne Niemarkt, Hendrik Reiss, Irwin Simons, Sinno Van Pul, Carola
topic	covid:bacd7f60d08bda9b4c4a8b6a47bc729121e5ce85#this
Source	PMC
abstract	BACKGROUND: Although sedative premedication for endotracheal intubation is considered standard of care, less invasive surfactant administration (LISA) is often performed without sedative premedication. The aim of this study was to assess success rates, technical quality and vital parameters in LISA without sedative premedication. METHODS: Prospective observational study in 86 neonates <32 weeks’ gestation. LISA was performed according to a standardized protocol without use of sedative premedication. Outcome measures were success rates of LISA attempts, reasons for failure and quality of technical conditions. In 37 neonates, heart rate and oxygen saturation levels from 20 min before until 30 min after start of LISA were collected. RESULTS: In 48% of LISAs the first attempt failed and in 34% quality of technical conditions was inadequate. The success rate was significantly correlated with quality of technical conditions and experience of the performer. Desaturations <80% occurred in 54% of patients while bradycardia <80/min did not occur. CONCLUSION: This study shows a relatively low success rate of the first attempt of LISA, frequent inadequacy of technical quality and frequent oxygen desaturations. These effects may be improved by the use of sedative premedication.
has issue date	2019-08-27(xsd:dateTime)
bibo:doi	10.1038/s41390-019-0552-z
bibo:pmid	31450233
has license	no-cc
sha1sum (hex)	bacd7f60d08bda9b4c4a8b6a47bc729121e5ce85
schema:url	https://doi.org/10.1038/s41390-019-0552-z
resource representing a document's title	Quality assessment and response to less invasive surfactant administration (LISA) without sedation
has PubMed Central identifier	PMC7223491
has PubMed identifier	31450233
schema:publication	Pediatr Res
resource representing a document's body	covid:bacd7f60d08bda9b4c4a8b6a47bc729121e5ce85#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/bacd7f60d08bda9b4c4a8b6a47bc729121e5ce85
is schema:about of	named entity 'success' named entity 'technical' named entity 'Although' named entity 'LISA' named entity 'LOW' named entity 'COLLECTED' named entity 'RATES' named entity 'FAILURE' named entity 'TECHNICAL QUALITY' named entity 'VITAL' named entity 'PERFORMER' named entity 'QUALITY' named entity 'PREMEDICATION' named entity 'OCCUR' covid:arg/bacd7f60d08bda9b4c4a8b6a47bc729121e5ce85 named entity 'premedication' named entity 'improved' named entity 'performed' named entity 'weeks' named entity 'start' named entity 'LISA' named entity 'RESULTS' named entity 'study' named entity 'measures' named entity 'min' named entity 'LISA' named entity 'Outcome measures' named entity 'oxygen' named entity 'endotracheal intubation' named entity 'sedative' named entity 'LISA' named entity 'neonates' named entity 'premedication' named entity 'LISA' named entity 'premedication' named entity 'oxygen saturation' named entity 'LISA' named entity 'starting time' named entity 'laryngoscopy' named entity 'endotracheal tube' named entity 'desaturations' named entity 'respiratory support' named entity 'respiratory drive' named entity 'premedicated' named entity 'laryngoscopy' named entity 'surfactant' named entity 'premedication' named entity 'birth weight' named entity 'premedication' named entity 'loading dose' named entity 'LISA' named entity 'randomized controlled trial' named entity 'LISA' named entity 'vital parameters' named entity 'flow chart' named entity 'neonatologist' named entity 'Parma' named entity 'intubations' named entity 'oxygen saturation' named entity 'premedication' named entity 'increase in heart rate' named entity 'vocal cords' named entity 'respiratory drive' named entity 'catheter' named entity 'oxygen saturation' named entity 'desaturations' named entity 'oxygen saturation' named entity 'laryngoscope' named entity 'catheter' named entity 'mechanical ventilation' named entity 'desaturations' named entity 'surfactant' named entity 'adverse events'

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