About: Viral bronchiolitis in children: A common condition with few therapeutic options()

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral bronchiolitis in children: A common condition with few therapeutic options()
Creator	Midulla, F Alessandroni, C Ferrara, M Gentile, F Grande, M Nicolai, A Schiavariello, C
Source	Elsevier; Medline; PMC
abstract	Even though bronchiolitis is a disease that has been recognized for many years, there are still few therapeutic strategies beyond supportive therapies. Bronchiolitis is the most frequent cause of hospital admission in children less than 1 year of age. The incidence is estimated to be about 150° million cases a year worldwide, and 2–3% of these cases require hospitalization. It is acknowledged that viruses cause bronchiolitis, but most of the studies focus on RSV. The RSV causes a more severe form of bronchiolitis in children with risk factors including prematurity, cardiovascular disease and immunodeficiency. Other viruses involved in causing bronchiolitis include RV, hMPV, hBoV and co-infections. The RV seems to be associated with a less severe acute disease, but there is a correlation between the early infection and subsequent wheezing bronchitis and asthma in later childhood and adulthood. The supportive therapies used are intravenous fluids and oxygen supplement administered by nasal cannula or CPAP in most complicated patients. Additional pharmacological therapies include epinephrine, 3% hypertonic saline and corticosteroids. The Epinephrine seems to have the greatest short-term benefits and reduces the need of hospital admission, whereas hypertonic saline and corticosteroids seem to reduce the length of hospital stay. As bronchiolitis is such a prevalent disease in children and RV seems to play an important role, perhaps more studies should center around the RV's contribution to the initial disease and following pathology.
has issue date	2013-08-21(xsd:dateTime)
bibo:doi	10.1016/j.earlhumdev.2013.07.016
bibo:pmid	23972293
has license	no-cc
sha1sum (hex)	bb0c0c2b370334c1264308db5150084813aa561a
schema:url	https://doi.org/10.1016/j.earlhumdev.2013.07.016
resource representing a document's title	Viral bronchiolitis in children: A common condition with few therapeutic options()
has PubMed Central identifier	PMC7130661
has PubMed identifier	23972293
schema:publication	Early Hum Dev
resource representing a document's body	covid:bb0c0c2b370334c1264308db5150084813aa561a#body_text
is schema:about of	named entity 'THERAPEUTIC' named entity 'CPAP' named entity 'asthma' named entity 'bronchiolitis' named entity 'CHILDREN' named entity 'A COMMON' named entity 'PLAY' named entity 'LESS THAN 1 YEAR' named entity '2-3' named entity 'SEVERE' named entity 'RISK FACTORS' named entity 'FOCUS' named entity '27S' named entity 'CAUSES' named entity 'VIRUSES' named entity 'NEED' named entity 'ASTHMA' named entity 'STRATEGIES' named entity 'BEYOND' named entity 'IMMUNODEFICIENCY' named entity 'OXYGEN' named entity 'PREVALENT' named entity 'CPAP' named entity 'INVOLVED' named entity 'CO-INFECTIONS' named entity 'RSV' named entity 'HOSPITAL ADMISSION' named entity '150' named entity 'YEARS' named entity 'ROLE' named entity 'SUPPORTIVE' named entity 'IMPORTANT' named entity 'BENEFITS' named entity 'THERAPIES' named entity 'WORLDWIDE' named entity 'HOSPITALIZATION' named entity 'VIRAL BRONCHIOLITIS' named entity 'CONTRIBUTION' named entity 'WHEEZING' named entity 'LATER CHILDHOOD' named entity 'CENTER' named entity 'INCLUDING' named entity 'GREATEST' named entity 'MOST OF' named entity 'FREQUENT' named entity 'CONDITION' named entity 'USED' named entity 'ASSOCIATED WITH' named entity 'ADMINISTERED' named entity 'CAUSING' named entity 'CARDIOVASCULAR DISEASE' named entity 'EPINEPHRINE' named entity 'PHARMACOLOGICAL' named entity 'PATHOLOGY' named entity 'BUT' named entity 'DISEASE' named entity 'AGE' named entity 'SHORT-TERM' named entity 'HYPERTONIC SALINE' named entity 'ADULTHOOD' named entity 'HMPV' named entity 'CHILDREN' named entity 'INCLUDE' named entity 'INCIDENCE' named entity 'NASAL CANNULA' named entity 'SUPPLEMENT' named entity 'CORTICOSTEROIDS' named entity 'LENGTH OF HOSPITAL STAY' named entity 'CASES' named entity 'FORM' named entity 'STUDIES' named entity 'INITIAL' named entity 'ADDITIONAL' named entity 'ACUTE DISEASE' named entity 'PREMATURITY'

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