About: Clinical and Molecular Epidemiology of Human Bocavirus in Respiratory and Fecal Samples from Children in Hong Kong

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About: Clinical and Molecular Epidemiology of Human Bocavirus in Respiratory and Fecal Samples from Children in Hong Kong Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical and Molecular Epidemiology of Human Bocavirus in Respiratory and Fecal Samples from Children in Hong Kong
Creator	Yuen, Kwok-Yung Lau, Yu-Lung Chan, Kwok-Hung Zhou, Boping Yip, Cyril So, Lok-Yee Que, Tak-Lun Au-Yeung, Rex Lau, Susanna Woo, Patrick Lee, Rodney
topic	covid:bb8dfdbcb3c6cc7cbf1c848c43b07838c42f9269#this
Source	Medline; PMC
abstract	Background. Human bocavirus (HBoV) is a recently discovered parvovirus associated with respiratory tract infections in children. We conducted the first systematic prospective clinical and molecular study using nasopharyngeal aspirates (NPAs) and fecal samples. Methods. NPAs negative for influenza virus, parainfluenza virus, respiratory syncytial virus, adenovirus, and coronavirus and fecal samples from patients with acute gastroenteritis were included. On the basis of results from a pilot study using 400 NPAs from all age groups, a prospective 12-month study was conducted to detect HBoV in 1200 NPAs and 1435 fecal samples from patients <18 years old by polymerase chain reaction. The complete genome sequences of HBoVs from 12 NPAs and 12 fecal samples were determined. Results. Of the 400 NPAs collected in the pilot study, 20 (5.0%) were found to contain HBoV, all from children <5 years old. In the subsequent prospective study of pediatric patients, HBoV was detected in 83 (6.9%) of 1200 NPAs. Upper and lower respiratory tract infections were equally common. HBoV was detected in 30 (2.1%) of 1435 fecal samples. Fever and watery diarrhea were the most common symptoms. The seasonality of HBoV in NPAs and fecal samples was similar. Codetection with other pathogens occurred in 33% and 56% of NPAs and fecal samples, respectively, from patients with HBoV infection. Genomes of HBoVs from NPAs and fecal samples displayed minimal sequence variations. Conclusions. HBoV was detected in fecal specimens in children with acute gastroenteritis. A single lineage of HBoV was associated with both respiratory tract and enteric infections.
has issue date	2007-10-01(xsd:dateTime)
bibo:doi	10.1086/521310
bibo:pmid	17763318
has license	no-cc
sha1sum (hex)	bb8dfdbcb3c6cc7cbf1c848c43b07838c42f9269
schema:url	https://doi.org/10.1086/521310
resource representing a document's title	Clinical and Molecular Epidemiology of Human Bocavirus in Respiratory and Fecal Samples from Children in Hong Kong
has PubMed Central identifier	PMC7111856
has PubMed identifier	17763318
schema:publication	J Infect Dis
resource representing a document's body	covid:bb8dfdbcb3c6cc7cbf1c848c43b07838c42f9269#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/bb8dfdbcb3c6cc7cbf1c848c43b07838c42f9269
is schema:about of	named entity 'HUMAN BOCAVIRUS' named entity 'Human' named entity 'CLINICAL' named entity 'MOLECULAR EPIDEMIOLOGY' named entity 'CHILDREN' named entity 'RESPIRATORY' named entity 'HONG KONG' named entity 'FECAL' named entity 'SAMPLES' named entity 'LRTI' named entity 'HBoV' named entity 'HBoV' named entity 'Europe' named entity 'viruses' named entity 'HBoV' named entity 'respiratory symptoms' named entity 'respiratory symptoms' named entity 'human coronaviruses' named entity 'epidemiology' named entity 'PCR' named entity 'virus' named entity 'HBoV' named entity 'protein' named entity 'HBoV' named entity 'pathogens' named entity 'URTI' named entity 'LRTI' named entity 'LRTI' named entity 'PCR' named entity 'PCR' named entity 'pathogens' named entity 'agarose gel electrophoresis' named entity 'asymptomatic' named entity 'gene' named entity 'fever' named entity 'protein' named entity 'clinical features' named entity 'urinary tract infection' named entity 'North America' named entity 'HBoV' named entity 'HBoV' named entity 'mucus' named entity 'Parvoviridae' named entity 'vomiting' named entity 'HBoV' named entity 'URTI' named entity 'virus' named entity 'asthma exacerbations' named entity 'parvovirus' named entity 'pneumonia' named entity 'Asia' named entity 'direct immunofluorescence' named entity 'rhinovirus' named entity 'intussusception' named entity 'phylogenetic analysis' named entity 'coronaviruses' named entity 'underlying diseases' named entity 'diarrhea' named entity 'HBoV' named entity 'vomiting' named entity 'pediatric patients' named entity 'HKU1' named entity 'acute bronchitis' named entity 'HBoV' named entity 'HBoV' named entity 'respiratory tract' named entity 'PCR' named entity 'HBoV' named entity 'watery diarrhea'

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