About: Circovirus in Tissues of Dogs with Vasculitis and Hemorrhage

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About: Circovirus in Tissues of Dogs with Vasculitis and Hemorrhage Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Circovirus in Tissues of Dogs with Vasculitis and Hemorrhage
Creator	Li, Linlin Delwart, Eric Wang, Chunlin Gaffney, Patricia Kubiski, Steven Zhu, Kevin Leutenegger, Christian Delwart, E Francisco, San Li, ( Marks, Stanley Pesavento, Patricia Cruz, F Cruz, Florante Gaffney, P Kubiski, S Marks, S Mcgraw, Sabrina Pesaven, P
Source	Medline; PMC
abstract	We characterized the complete genome of a novel dog circovirus (DogCV) from the liver of a dog with severe hemorrhagic gastroenteritis, vasculitis, and granulomatous lymphadenitis. DogCV was detected by PCR in fecal samples from 19/168 (11.3%) dogs with diarrhea and 14/204 (6.9%) healthy dogs and in blood from 19/409 (3.3%) of dogs with thrombocytopenia and neutropenia, fever of unknown origin, or past tick bite. Co-infection with other canine pathogens was detected for 13/19 (68%) DogCV-positive dogs with diarrhea. DogCV capsid proteins from different dogs varied by up to 8%. In situ hybridization and transmission electron microscopy detected DogCV in the lymph nodes and spleens of 4 dogs with vascular compromise and histiocytic inflammation. The detection of a circovirus in tissues of dogs expands the known tropism of these viruses to a second mammalian host. Our results indicate that circovirus, alone or in co-infection with other pathogens, might contribute to illness and death in dogs.
has issue date	2013-04-01(xsd:dateTime)
bibo:doi	10.3201/eid1904.121390
bibo:pmid	23628223
has license	no-cc
sha1sum (hex)	bc652839250b03af000623dec894399f63d8203b
schema:url	https://doi.org/10.3201/eid1904.121390
resource representing a document's title	Circovirus in Tissues of Dogs with Vasculitis and Hemorrhage
has PubMed Central identifier	PMC3647419
has PubMed identifier	23628223
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:bc652839250b03af000623dec894399f63d8203b#body_text
is schema:about of	named entity 'tropism' covid:arg/bc652839250b03af000623dec894399f63d8203b named entity 'dogs' named entity 'blood' named entity 'dog' named entity 'host' named entity 'fecal' named entity 'circovirus' named entity 'tick bite' named entity 'proteins' named entity 'PCR' named entity 'vasculitis' named entity 'tropism' named entity 'tick bite' named entity 'transmission electron microscopy' named entity 'hybridization' named entity 'dog' named entity 'hemorrhagic gastroenteritis' named entity 'fever of unknown origin' named entity 'viruses' named entity 'PCR' named entity 'capsid proteins' named entity 'circovirus' named entity 'lymphadenitis' named entity 'Hemorrhage' named entity 'electron-dense' named entity 'swine' named entity 'vomiting' named entity 'protozoal' named entity 'Anatomic Pathology' named entity 'Medical Teaching' named entity 'nonenveloped' named entity 'capsids' named entity 'Gyrovirus' named entity 'GenBank' named entity 'primer walking' named entity 'GenBank' named entity 'canine' named entity 'Carlsbad, CA' named entity 'formamide' named entity 'dry ice' named entity 'pathogen' named entity 'tetraparesis' named entity 'Germany' named entity 'vasculitis' named entity '37°C' named entity 'fibrinoid' named entity 'genome' named entity 'Salmonella spp' named entity 'UC Davis School of Veterinary Medicine' named entity 'genus' named entity 'formamide' named entity 'tissue samples' named entity 'rolling circle replication' named entity 'hemorrhage' named entity 'Synthetic DNA' named entity 'hybridization' named entity 'histiocytic' named entity 'Pittsburgh' named entity 'intergenic region' named entity 'gastrointestinal tract' named entity 'kidneys' named entity 'multinucleate'

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