About: Countrywide Survey for MERS-Coronavirus Antibodies in Dromedaries and Humans in Pakistan

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About: Countrywide Survey for MERS-Coronavirus Antibodies in Dromedaries and Humans in Pakistan Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Countrywide Survey for MERS-Coronavirus Antibodies in Dromedaries and Humans in Pakistan
Creator	Chen, Jing Zhu, Yan Shi, Zheng-Li Zhang, Wei Luo, Yun Hu, Bing-Jie Khan, Iahtasham Khan, Saeed Sadia, Halima Tahir, Usman Taj, Zeeshan Waruhiu, Cecilia Yan, Bing Zohaib, Ali Athar, Ammar Awais-Ur-, • Bilal, • Cn, Corman, Max Ikram, • Khan, Ahmed Li, • Mansoor, Khalid Muhammad, • Naeem, Ahsan Qureshi, Asif Sajid, Sohail Saqib, • Sial, Rahman Tayyab, Haleem Victor, • Yang, • Xing-Lou
Source	Medline; PMC
abstract	Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic pathogen capable of causing severe respiratory disease in humans. Although dromedary camels are considered as a major reservoir host, the MERS-CoV infection dynamics in camels are not fully understood. Through surveillance in Pakistan, nasal (n = 776) and serum (n = 1050) samples were collected from camels between November 2015 and February 2018. Samples were collected from animal markets, free-roaming herds and abattoirs. An in-house ELISA was developed to detect IgG against MERS-CoV. A total of 794 camels were found seropositive for MERS-CoV. Prevalence increased with the age and the highest seroprevalence was recorded in camels aged > 10 years (81.37%) followed by those aged 3.1–10 years (78.65%) and ≤ 3 years (58.19%). Higher prevalence was observed in female (78.13%) as compared to male (70.70%). Of the camel nasal swabs, 22 were found to be positive by RT-qPCR though with high Ct values. Moreover, 2,409 human serum samples were also collected from four provinces of Pakistan during 2016–2017. Among the sampled population, 840 humans were camel herders. Although we found a high rate of MERS-CoV antibody positive dromedaries (75.62%) in Pakistan, no neutralizing antibodies were detected in humans with and without contact to camels.
has issue date	2018-10-01(xsd:dateTime)
bibo:doi	10.1007/s12250-018-0051-0
bibo:pmid	30311100
has license	bronze-oa
sha1sum (hex)	bc86260d40e83083be6fd98b99b27894bf9524b7
schema:url	https://doi.org/10.1007/s12250-018-0051-0
resource representing a document's title	Countrywide Survey for MERS-Coronavirus Antibodies in Dromedaries and Humans in Pakistan
has PubMed Central identifier	PMC6235758
has PubMed identifier	30311100
schema:publication	Virologica Sinica
resource representing a document's body	covid:bc86260d40e83083be6fd98b99b27894bf9524b7#body_text
is schema:about of	named entity 'CORONAVIRUS' named entity 'Samples' named entity 'camels' named entity 'dromedary' named entity 'animal' named entity 'February' named entity 'Countrywide' named entity 'SAMPLED' named entity 'IN-HOUSE' named entity 'COLLECTED' named entity 'FREE' named entity 'MALE' named entity 'PAKISTAN' named entity 'SEROPREVALENCE' named entity '3.1' named entity 'COMPARED' named entity 'FOUND' covid:arg/bc86260d40e83083be6fd98b99b27894bf9524b7 named entity 'DETECTED' named entity '2015' named entity '2018' named entity 'TO DETECT' named entity 'HUMANS' named entity 'RT-QPCR' named entity 'HUMAN SERUM' named entity 'HIGHER' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'INFECTION' named entity 'OBSERVED' named entity 'DROMEDARY' named entity 'NASAL SWABS' named entity 'MERS' named entity 'SURVEY' named entity 'ANTIBODIES' named entity 'FEBRUARY' named entity 'FEMALE' named entity 'CONTACT' named entity 'NEUTRALIZING ANTIBODIES' named entity 'AGE' named entity 'POSITIVE' named entity 'ABATTOIRS' named entity 'ANTIBODY POSITIVE' named entity 'ANIMAL' named entity 'TOTAL' named entity 'HIGH RATE' named entity 'SURVEILLANCE' named entity 'CAMEL' named entity 'CAUSING' named entity 'RECORDED' named entity 'DROMEDARIES'

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