About: Clinical Features and Outcomes of 105 Hospitalized patients with COVID-19 in Seattle, Washington

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About: Clinical Features and Outcomes of 105 Hospitalized patients with COVID-19 in Seattle, Washington Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Features and Outcomes of 105 Hospitalized patients with COVID-19 in Seattle, Washington
Creator	Jerome, Keith Nalla, Arun Huang, Meei-Li Chu, Helen Kim, H Green, Margaret Mcculloch, Denise Cohen, Seth Blain, Michela Greninger, Alex Neme, Santiago Buckner, Frederick Atluri, Vidya Mcguffin, Sarah
Source	Medline; PMC
abstract	BACKGROUND: Washington State served as the initial epicenter of the SARS-CoV-2 pandemic in the United States. An understanding of the risk factors and clinical outcomes of hospitalized patients with COVID-19 may provide guidance for management. METHODS: All laboratory-confirmed COVID-19 cases in adults admitted to an academic medical center in Seattle, WA between March 2 and March 26, 2020 were included. We evaluated individuals with and without severe disease, defined as admission to the intensive care unit or death. RESULTS: One-hundred-five COVID-19 patients were hospitalized. Thirty-five percent were admitted from a senior home or skilled nursing facility. The median age was 69 years and half were women. Three or more comorbidities were present in 55% of patients, with hypertension (59%), obesity (47%), cardiovascular disease (38%) and diabetes (33%) being the most prevalent. Most (63%) had symptoms for 5 days or longer prior to admission. Only 39% had fever in the first 24 hours, whereas 41% had hypoxia at admission. Seventy-three percent of patients had lymphopenia. Of 50 samples available for additional testing, no viral coinfections were identified. Severe disease occurred in 49%. Eighteen percent of patients were placed on mechanical ventilation and the overall mortality rate was 33%. CONCLUSIONS: During the early days of the COVID-19 epidemic in Washington State, the disease had its greatest impact on elderly patients with medical comorbidities. We observed high rates of severe disease and mortality in our hospitalized patients.
has issue date	2020-05-22(xsd:dateTime)
bibo:doi	10.1093/cid/ciaa632
bibo:pmid	32444880
has license	no-cc
sha1sum (hex)	bcc802d1e0f4aa8d7969da031d1bf493ece49a6a
schema:url	https://doi.org/10.1093/cid/ciaa632
resource representing a document's title	Clinical Features and Outcomes of 105 Hospitalized patients with COVID-19 in Seattle, Washington
has PubMed Central identifier	PMC7314181
has PubMed identifier	32444880
schema:publication	Clin Infect Dis
resource representing a document's body	covid:bcc802d1e0f4aa8d7969da031d1bf493ece49a6a#body_text
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