About: Aetiology of Balkan nephropathy: A reapprisal after 30 years

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Aetiology of Balkan nephropathy: A reapprisal after 30 years
Creator	Radovanovic, Z
Source	Medline; PMC
abstract	Balkan nephropathy (BN) has been a complete aetiological puzzle for many years. Intense research produced many controversial results, but also helped some clues to be traced. Thus, it became rather obvious that the disease is caused by environmental factors (though it may be, to some extent, genetically controlled). Among live agents, slow viruses are the only (and theoretically very attractive) possible cause of both BN and urothelial tumours, which occur frequently in BN endemic areas. Apart from occasional visualization of virus-like particles, other evidence supporting this hypothesis has been lacking. The role of biological products, particularly fungal toxins, needs to be further defined. An excess of any heavy metal or radioactive substance as a cause of BN is very unlikely indeed; however, a deficiency of a bio-essential element could not be ruled out. Many epidemiological data indicate that water might be a transmitter of the agent(s). A wide range of ions and minerals have been incriminated, but up to now most of the studies have provided negative or inconclusive results. Organic compounds in well water have never been sufficiently considered. Another ignored area are unstable and, particularly, photosensitive substances. Fertilizers, pesticides, analgesics, local herbs and teas have no causal relation to BN.
has issue date	1989-01-01(xsd:dateTime)
bibo:doi	10.1007/bf00144840
bibo:pmid	2676585
has license	no-cc
sha1sum (hex)	bcd3174513bd64bc0d05ae1e60425d037eee182e
schema:url	https://doi.org/10.1007/bf00144840
resource representing a document's title	Aetiology of Balkan nephropathy: A reapprisal after 30 years
has PubMed Central identifier	PMC7087977
has PubMed identifier	2676585
schema:publication	Eur J Epidemiol
resource representing a document's body	covid:bcd3174513bd64bc0d05ae1e60425d037eee182e#body_text
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