About: Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia

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About: Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia
Creator	Daszak, Peter Jain, Komal Briese, Thomas Karesh, William Jabado, Omar Mishra, Nischay Alagaili, Abdulaziz Katze, Michael Lipkin, W Mohammed, Osama Zalmout, Iyad
Source	Medline; PMC
abstract	Complete Middle East respiratory syndrome coronavirus (MERS-CoV) genome sequences were obtained from nasal swabs of dromedary camels sampled in the Kingdom of Saudi Arabia through direct analysis of nucleic acid extracts or following virus isolation in cell culture. Consensus dromedary MERS-CoV genome sequences were the same with either template source and identical to published human MERS-CoV sequences. However, in contrast to individual human cases, where only clonal genomic sequences are reported, detailed population analyses revealed the presence of more than one genomic variant in individual dromedaries. If humans are truly infected only with clonal virus populations, we must entertain a model for interspecies transmission of MERS-CoV wherein only specific genotypes are capable of passing bottleneck selection.
has issue date	2014-04-29(xsd:dateTime)
bibo:doi	10.1128/mbio.01146-14
bibo:pmid	24781747
has license	cc-by-nc-sa
sha1sum (hex)	bddfc27eab5ed01ee09fcab0f11fd6c0a0bd458e
schema:url	https://doi.org/10.1128/mbio.01146-14
resource representing a document's title	Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia
has PubMed Central identifier	PMC4010836
has PubMed identifier	24781747
schema:publication	mBio
resource representing a document's body	covid:bddfc27eab5ed01ee09fcab0f11fd6c0a0bd458e#body_text
is schema:about of	named entity 'CAMELS' named entity 'SPECIFIC' named entity 'HUMANS' named entity 'REVEALED' named entity 'VIRUS ISOLATION' named entity 'GENOMIC' named entity 'CONTRAST' named entity 'KINGDOM OF SAUDI ARABIA' named entity 'SEQUENCES' named entity 'CONSENSUS' named entity 'INDIVIDUAL' named entity 'OBTAINED' named entity 'SAMPLED' named entity 'CLONAL' named entity 'WHERE' named entity 'CELL CULTURE' named entity 'INFECTED' named entity 'coronavirus' named entity 'Middle East respiratory syndrome' named entity 'published' named entity 'dromedary' named entity 'genomic' named entity 'MERS-COV' named entity 'REVEALED' named entity 'REPORTED' named entity 'DIRECT' named entity 'INCLUDE' named entity 'DROMEDARY' named entity 'CULTURED' named entity 'VIRUS' named entity 'CAPABLE' named entity 'MODEL' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'HUMAN' named entity 'GENOME ANALYSIS' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'SAUDI ARABIA' named entity 'ISOLATES' named entity 'TRANSMISSION' named entity 'PRESENCE OF' named entity 'DROMEDARY' named entity 'SOURCE' named entity 'DETAILED' named entity 'CAMELS' named entity 'COMPLETE' named entity 'GENOME' named entity 'NASAL SWABS' named entity 'PUBLISHED' named entity 'MORE THAN ONE' named entity 'NUCLEIC ACID' named entity 'GENOTYPES' named entity 'EITHER' named entity 'IDENTICAL' named entity 'ANALYSIS' named entity 'SELECTION' named entity 'QUASISPECIES' named entity 'VIRUS' named entity 'FOLLOWING' named entity 'POPULATION' named entity 'CASES' named entity 'HUMAN' named entity 'VARIANT' named entity 'EXTRACTS' named entity 'TEMPLATE' named entity 'acid' named entity 'bottleneck' named entity 'sequences' named entity 'revealed' named entity 'dromedaries' named entity 'model' named entity 'infected'

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