About: Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco
Creator	Bassat, Quique Gern, James Benmessaoud, Rachid Jroundi, Imane Mahraoui, Chafiq Moraleda, Cinta Bizzintino, Joelene Goldblatt, Jack Khoo, Siew-Kim Laing, Ingrid Lehmann, Deborah Zhang, Guicheng Le Souëf, Peter Annamalay, Alicia
Source	PMC
abstract	Human rhinovirus (RV) is commonly associated with severe acute lower respiratory infections (ALRI) in children. We aimed to describe the distribution of RV species and associations between RV species and clinical features in children hospitalized with clinically severe pneumonia (CSP) in Morocco. Nasopharyngeal aspirates (NPAs) were collected from 700 children, 2–59 months of age, admitted with CSP to the Hôpital d'Enfants de Rabat in Morocco. At least one respiratory virus was identified in 92% of children, of which RV was the most common (53%). PCR assays, sequencing, and phylogenetic tree analyses were carried out on 183 RV‐positive NPAs to determine RV species and genotypes. Of 157 successfully genotyped NPAs, 60 (38.2%) were RV‐A, 8 (5.1%) were RV‐B, and 89 (56.7%) were RV‐C. Wheezing and cyanosis were more common in RV‐C‐positive than RV‐A‐positive children (80.9% vs. 56.7%; P = 0.001 for wheezing and 10.1% vs. 0%; P = 0.011 for cyanosis). Physician's discharge diagnosis of pneumonia was more frequent among RV‐A‐positive (40.0%) than RV‐C‐positive children (20.2%; P = 0.009). RV‐A and RV‐C showed distinct seasonal patterns. Our findings suggest that RV‐C is associated with wheezing illness while RV‐A is associated with pneumonia. J. Med. Virol. 89:582–588, 2017. © 2016 Wiley Periodicals, Inc.
has issue date	2016-09-30(xsd:dateTime)
bibo:doi	10.1002/jmv.24684
bibo:pmid	27677921
has license	no-cc
sha1sum (hex)	be10fdf3b321a653d2760189a72f046e89e5f902
schema:url	https://doi.org/10.1002/jmv.24684
resource representing a document's title	Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco
has PubMed Central identifier	PMC7166858
has PubMed identifier	27677921
schema:publication	J Med Virol
resource representing a document's body	covid:be10fdf3b321a653d2760189a72f046e89e5f902#body_text
is schema:about of	named entity 'DISCHARGE DIAGNOSIS' named entity 'RESPIRATORY VIRUS' named entity 'SPECIES' named entity 'FINDINGS' named entity '700' named entity 'ADMITTED' named entity 'NASOPHARYNGEAL' named entity 'HOSPITALIZED CHILDREN' named entity 'RHINOVIRUS C' named entity 'severe' named entity 'cyanosis' named entity 'Human rhinovirus' named entity 'determine' named entity 'genotypes' named entity 'frequent' named entity 'pneumonia' named entity 'sequencing' named entity 'NPAs' named entity 'NPAs' named entity 'carried' named entity 'Rhinovirus A' named entity 'RV-C' named entity 'RV-C' named entity 'PCR' named entity 'Morocco' named entity 'RV-C' named entity 'wheezing' named entity 'ALRI' named entity 'A-positive' named entity 'Morocco' named entity 'hospitalized' named entity 'Viral' named entity 'Rabat' named entity 'SPSS' named entity 'wheeze' named entity 'genotypes' named entity 'genotyping' named entity 'SPSS' named entity 'pneumonia' named entity 'diagnostic criteria' named entity 'WHO' named entity 'A-positive' named entity 'viruses' named entity 'Moroccan' named entity 'respiratory infections' named entity 'A-positive' named entity 'clinical features' named entity 'Perth' named entity 'severe pneumonia' named entity 'RV-C' named entity 'RV-C' named entity 'clinical features' named entity 'serological' named entity 'coding region' named entity 'WHO' named entity 'RNA' named entity 'Morocco' named entity 'China' named entity 'nasopharyngeal' named entity 'RV-C' named entity 'virus' named entity 'RV-C' named entity 'Clinical diagnoses' named entity 'viruses' named entity 'lower respiratory tract infections' named entity 'CSP' named entity 'RV-C' named entity 'RV-C'

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