About: Clinical Time Features and Chest Imaging of 85 Patients With COVID-19 in Zhuhai, China

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Clinical Time Features and Chest Imaging of 85 Patients With COVID-19 in Zhuhai, China
Creator	Xia, Jinyu Ding, Li Li, Xinghua Liu, Xi Xie, Jianfeng Zhang, Zhongheng Chen, Gongqi Liu, Zhuobing Luo, Wentao Luo, Xiaoqing Moghnieh, Rima Zhao, Chaohui
source	Medline; PMC
abstract	Background: An outbreak of SARS-CoV-2 infections began in Wuhan, China, and quickly spread to the entire country. We sought to delineate the time features of clinical symptoms, virological conversion, and chest radiological abnormalities in individuals infected with this virus in Zhuhai, China. Methods: In this retrospective study, we assessed 85 confirmed cases of COVID-19 in the Fifth Hospital of Sun Yat-sen University, Zhuhai, from the 17th of January to the 11th of February 2020. Outcomes were followed up until the 24th of February 2020. Results: The median age of the 85 patients with COVID-19 was 43 years (range, 1–80); 56.5% (48/85) were female. The median time from the last known contact to the first SARS-CoV-2 positive test result was 8 days (0–18). The time to throat swab negativity for SARS-CoV-2 ranged from 5 to 36 days after illness onset. Patients with abnormal chest imaging findings on admission were older than those with normal imaging findings (median age, 50 [3-80] vs. 37 [1-69], P = 0.031). Among patients with lung changes on admission, the risk of lesions was 13.8 times greater in the left lower lobe than in the right middle lobe. Most lung lesions appeared within 2 weeks of onset (median 4–5 days). The overall rates of lesions in the right upper/middle/lower lobe and left upper/lower lobe were 47.1, 30.6, 62.4% as well as 49.4 and 63.5%, respectively. Conclusions: The incubation period of SARS-CoV-2 may be longer than 14 days; thus, medical surveillance after contact is required for longer than this. The predominant sites of lung lesions are both lower lungs, whereas the lowest risk region is the right middle lobe.
has issue date	2020-05-08(xsd:dateTime)
bibo:doi	10.3389/fmed.2020.00209
bibo:pmid	32574321
has license	cc-by
sha1sum (hex)	bf3bd613ef4d9084caa13029649419fa46049466
schema:url	https://doi.org/10.3389/fmed.2020.00209
resource representing a document's title	Clinical Time Features and Chest Imaging of 85 Patients With COVID-19 in Zhuhai, China
has PubMed Central identifier	PMC7225607
has PubMed identifier	32574321
schema:publication	Front Med (Lausanne)
resource representing a document's body	covid:bf3bd613ef4d9084caa13029649419fa46049466#body_text
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