About: Rapid multiplex microfiber-based immunoassay for anti-MERS-CoV antibody detection

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About: Rapid multiplex microfiber-based immunoassay for anti-MERS-CoV antibody detection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Rapid multiplex microfiber-based immunoassay for anti-MERS-CoV antibody detection
Creator	Ryo, Akihide Yamaoka, Yutaro Kushiro, Keiichiro Takai, Madoka Hoy, Carlton
source	Elsevier; Medline; PMC
abstract	On-site multiplex biosensors for innate immunity antibodies are ideal tools for monitoring health status of individuals against various diseases. This study introduces a novel antibody immunoassay testing platform incorporating microfiber-based arrays of antigens to capture specific antibodies. The fabrication and setup of the device revolved around electrospun polystyrene (ESPS) microfibers that act as three-dimensional membrane filters, capable of rapid and multifold analyte capture. In particular, the ESPS microfibers were patterned through localized oxygen plasma to create hydrophilic zones that facilitate fluid flows and immobilizations of antigens. The bulk of this robust antibody immunoassay platform could be installed into a compact syringe-driven cassette device, which could perform multiplex antibody immunoassay for antibodies specifically against Middle East respiratory syndrome coronavirus (MERS-CoV) with rapid preparation amounting to a total of 5 min, as well as high sensitivity and specificity for the MERS-CoV down to 200 μg/mL.
has issue date	2019-10-14(xsd:dateTime)
bibo:doi	10.1016/j.sbsr.2019.100304
bibo:pmid	32289017
has license	no-cc
sha1sum (hex)	c06cc695e9fe227f6610e162bc2b18537c1779a1
schema:url	https://doi.org/10.1016/j.sbsr.2019.100304
resource representing a document's title	Rapid multiplex microfiber-based immunoassay for anti-MERS-CoV antibody detection
has PubMed Central identifier	PMC7104066
has PubMed identifier	32289017
schema:publication	Sens Biosensing Res
resource representing a document's body	covid:c06cc695e9fe227f6610e162bc2b18537c1779a1#body_text
is schema:about of	named entity 'study' named entity 'biosensors' named entity 'installed' named entity 'fluid flows' named entity 'Middle East respiratory syndrome' named entity 'antibody' named entity 'MULTIPLEX' named entity 'ESPS' named entity 'PARTICULAR' named entity 'ANTIBODY' named entity 'OXYGEN' named entity 'FLUID' named entity 'ACT' named entity 'ANALYTE' named entity 'BCG' named entity 'PLATFORM' named entity 'SENSITIVITY AND SPECIFICITY' named entity 'SETUP' named entity 'INNATE IMMUNITY' named entity 'FILTERS' named entity 'ANTIGENS' named entity 'VARIOUS' named entity 'INTRODUCES' named entity 'MERS-COV' named entity 'SITE' named entity 'CREATE' named entity 'SPECIFIC' named entity 'TESTING' named entity 'MEMBRANE' named entity 'ANTIBODIES' named entity 'ANTIBODY DETECTION' named entity 'FABRICATION' named entity 'FLOWS' named entity 'MONITORING' named entity 'TOTAL' named entity 'TOOLS' named entity 'CAPTURE' named entity 'STUDY' named entity 'PERFORM' named entity 'INDIVIDUALS' named entity 'COMPACT' named entity 'MICROFIBER' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'RAPID' named entity 'PREPARATION' named entity 'LOCALIZED' named entity 'HIGH SENSITIVITY' named entity 'CAPABLE' named entity 'ROBUST' named entity 'BASED' named entity 'RAPID' named entity 'MULTIPLEX' named entity 'COULD BE' named entity 'HEALTH STATUS' named entity 'BULK' named entity 'IMMUNOASSAY' named entity 'IDEAL' named entity 'NOVEL' named entity 'THREE-DIMENSIONAL' named entity 'POLYSTYRENE' named entity 'DISEASES' named entity 'HYDROPHILIC' named entity 'DEVICE' named entity 'CASSETTE DEVICE' named entity 'MIN' named entity '200' named entity 'BASED' named entity 'IMMUNOASSAY' named entity 'MICROFIBER' named entity 'BIOSENSORS' named entity 'PLASMA' covid:arg/c06cc695e9fe227f6610e162bc2b18537c1779a1 named entity 'min' named entity 'fabrication' named entity 'health' named entity 'antigens' named entity 'testing'

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