About: Exploitation of viral properties for intracellular delivery

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Exploitation of viral properties for intracellular delivery
Creator	Caraglia, Michele Falanga, Annarita Galdiero, Massimiliano Galdiero, Stefania Vitiello, Mariateresa Morelli, Giancarlo Grieco, Paolo
source	Medline; PMC
abstract	Nanotechnology is an expanding area of study with potentially pivotal applications in a discipline as medicine where new biomedical active molecules or strategies are continuously developing. One of the principal drawbacks for the application of new therapies is the difficulty to cross membranes that represent the main physiological barrier in our body and in all living cells. Membranes are selectively permeable and allow the selective internalization of substances; generally, they form a highly impermeable barrier to most polar and charged molecules, and represent an obstacle for drug delivery, limiting absorption to specific routes and mechanisms. Viruses provide attracting suggestions for the development of targeted drug carriers as they have evolved naturally to deliver their genomes to host cells with high fidelity. A detailed understanding of virus structure and their mechanisms of entry into mammalian cells will facilitate the development and analysis of virus‐based materials for medical applications. Copyright © 2014 European Peptide Society and John Wiley & Sons, Ltd.
has issue date	2014-05-30(xsd:dateTime)
bibo:doi	10.1002/psc.2649
bibo:pmid	24889153
has license	no-cc
sha1sum (hex)	c13881c75835603fcb84e2046c39dc11edd6149c
schema:url	https://doi.org/10.1002/psc.2649
resource representing a document's title	Exploitation of viral properties for intracellular delivery
has PubMed Central identifier	PMC7168031
has PubMed identifier	24889153
schema:publication	J Pept Sci
resource representing a document's body	covid:c13881c75835603fcb84e2046c39dc11edd6149c#body_text
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