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About:
Discovery of Diverse Rodent and Bat Pestiviruses With Distinct Genomic and Phylogenetic Characteristics in Several Chinese Provinces
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Discovery of Diverse Rodent and Bat Pestiviruses With Distinct Genomic and Phylogenetic Characteristics in Several Chinese Provinces
Creator
Liu, Qiyong
Canuti, Marta
Du, Jiang
Han, Yelin
Jin, Qi
Liu, Bo
Lu, Liang
Su, Haoxiang
Wu, Zhiqiang
Yang, Li
Zhang, Junpeng
Zhang, Shuyi
Zhu, Guangjian
Liu, Wu
Banyard, Ashley
Source
Medline; PMC
abstract
Bats and rodents are widely distributed worldwide and can be native or intermediate reservoirs of many important zoonotic viruses. Pestiviruses are a group of virus species of the genus Pestivirus under the family Flaviviridae that can infect a wide variety of artiodactylous hosts, including swine and ruminants. Two classic types of pestiviruses, bovine viral diarrhea virus and classical swine fever virus, are important causative agents of mild-to-severe disease in bovine and swine hosts, respectively, and cause tremendous economic losses in these industries. Recent reports revealed that bats and rodents could also act as natural hosts of pestiviruses and an atypical porcine pestivirus, which cause disease in piglets, showed a close genetic relationship with a specific bat pestivirus, RaPestV-1. This study aimed to describe the detection and characterization of novel pestiviruses from bats and rodents in different locations by analyzing the available bat and rodent virome data from throughout China. Two bat pestivirus species and four rodent pestivirus species that are distinct from other known viruses were identified and sequenced. These viruses were identified from two bat species and four rodent species in different Chinese provinces. There were two distinct lineages present in these viruses, that differ from artiodactylous pestivirus. These findings expand our understanding of the genetic diversity of pestiviruses in bats and rodents and suggest the presence of a diverse set of pestiviruses in non-artiodactylous hosts. This study may provide new insight for the prevention of future viral disease outbreaks originating from bats and rodents.
has issue date
2018-10-24
(
xsd:dateTime
)
bibo:doi
10.3389/fmicb.2018.02562
bibo:pmid
30405596
has license
cc-by
sha1sum (hex)
c1dc7422f1716cf0750c974a86d1c5ac0b48d810
schema:url
https://doi.org/10.3389/fmicb.2018.02562
resource representing a document's title
Discovery of Diverse Rodent and Bat Pestiviruses With Distinct Genomic and Phylogenetic Characteristics in Several Chinese Provinces
has PubMed Central identifier
PMC6207626
has PubMed identifier
30405596
schema:publication
Front Microbiol
resource representing a document's body
covid:c1dc7422f1716cf0750c974a86d1c5ac0b48d810#body_text
is
schema:about
of
named entity 'RODENT'
named entity 'Recent'
named entity 'causative'
named entity 'Bat'
named entity 'DISCOVERY'
named entity 'EXPAND'
named entity 'RODENT'
named entity 'DISTINCT'
named entity 'CHARACTERIZATION'
named entity 'DIFFERENT'
named entity 'SPECIFIC'
named entity 'NATURAL'
named entity 'VIRUSES'
named entity 'INTERMEDIATE'
named entity 'SEVERE DISEASE'
named entity 'CHINESE'
named entity 'FINDINGS'
named entity 'THESE'
named entity 'GENUS'
named entity 'PESTIVIRUSES'
named entity 'OUR'
named entity 'LOCATIONS'
named entity 'INFECT'
named entity 'SPECIES'
named entity 'BAT'
named entity 'DISTRIBUTED'
named entity 'PROVIDE'
named entity 'AVAILABLE'
named entity 'PRESENT'
named entity 'BOVINE'
named entity 'REPORTS'
named entity 'IMPORTANT'
named entity 'MILD'
named entity 'FAMILY FLAVIVIRIDAE'
named entity 'CAUSE'
named entity 'TO DESCRIBE'
named entity 'REVEALED'
named entity 'RODENTS'
named entity 'RELATIONSHIP'
named entity 'HOSTS'
named entity 'WIDE'
named entity 'NOVEL'
named entity 'NEW'
named entity 'WORLDWIDE'
named entity 'RODENT PESTIVIRUS'
named entity 'ACT'
named entity 'RESERVOIRS'
named entity 'NON-'
named entity 'SWINE'
named entity 'ECONOMIC'
named entity 'CHARACTERISTICS'
named entity 'FUTURE'
named entity 'SET'
named entity 'IDENTIFIED'
named entity 'BOVINE VIRAL DIARRHEA VIRUS'
named entity 'DIVERSE'
named entity 'DISTINCT'
named entity 'INCLUDING'
named entity 'TYPES'
named entity 'NATIVE'
named entity 'DETECTION'
named entity 'KNOWN'
named entity 'RUMINANTS'
named entity 'ATYPICAL PORCINE PESTIVIRUS'
named entity 'DATA'
named entity 'BATS'
named entity 'A GROUP'
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