About: Does virus–bacteria coinfection increase the clinical severity of acute respiratory infection?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Does virus–bacteria coinfection increase the clinical severity of acute respiratory infection?
Creator	Moreira, Suzana Duarte, Claudia Pereira, Luciane Raboni, Sonia Santos, Dos Damasio, Guilherme Dalla-Costa, Libera
Source	Medline; PMC
abstract	This retrospective cohort study investigated the presence of bacteria in respiratory secretions of patients hospitalized with acute respiratory infections and analyzed the impact of viral and bacterial coinfection on severity and the mortality rate. A total of 169 patients with acute respiratory infections were included, viruses and bacteria in respiratory samples were detected using molecular methods. Among all samples, 73.3% and 59.7% were positive for viruses and bacteria, respectively; 45% contained both virus and bacteria. Bacterial coinfection was more frequent in patients infected by community respiratory viruses than influenza A H1N1pdm (83.3% vs. 40.6%). The most frequently bacteria detected were Streptococcus pneumoniae and Haemophilus influenzae. Both species were co‐detected in 54 patients and identified alone in 22 and 21 patients, respectively. Overall, there were no significant differences in the period of hospitalization, severity, or mortality rate between patients infected with respiratory viruses alone and those coinfected by viruses and bacteria. The detection of mixed respiratory pathogens is frequent in hospitalized patients with acute respiratory infections, but its impact on the clinical outcome does not appear substantial. However, it should be noted that most of the patients received broad‐spectrum antibiotic therapy, which may have contributed to this favorable outcome. J. Med. Virol. 87:1456–1461, 2015. © 2015 Wiley Periodicals, Inc.
has issue date	2015-05-14(xsd:dateTime)
bibo:doi	10.1002/jmv.24210
bibo:pmid	25976175
has license	no-cc
sha1sum (hex)	c2a2c30873919a6e531fa51deba6365189ebe1e3
schema:url	https://doi.org/10.1002/jmv.24210
resource representing a document's title	Does virus–bacteria coinfection increase the clinical severity of acute respiratory infection?
has PubMed Central identifier	PMC7166438
has PubMed identifier	25976175
schema:publication	J Med Virol
resource representing a document's body	covid:c2a2c30873919a6e531fa51deba6365189ebe1e3#body_text
is schema:about of	named entity 'respiratory' named entity 'patients' named entity 'viral' named entity 'BACTERIA' named entity 'RESPIRATORY PATHOGENS' named entity 'COMMUNITY' named entity 'FREQUENT' named entity 'INVESTIGATED' named entity 'RESPIRATORY SAMPLES' named entity 'BACTERIA ' named entity 'BACTERIAL' named entity 'SIGNIFICANT' named entity 'DETECTION' named entity 'coinfected' named entity 'respiratory' named entity 'hospitalized' named entity 'frequent' named entity 'patients' named entity 'viruses' named entity 'Streptococcus' named entity 'respiratory' named entity 'viruses' named entity 'Coinfection' named entity 'bacteria' named entity 'acute respiratory infections' named entity 'influenza' named entity 'viruses' named entity 'bacteria' named entity 'bacteria' named entity 'virus' named entity 'viruses' named entity 'intensive care units' named entity 'multiplex PCR' named entity 'viruses' named entity 'bacteria' named entity 'Curitiba' named entity 'reverse transcription' named entity 'tuberculosis' named entity 'pneumonia' named entity 'coinfections' named entity 'H1N1 pandemic' named entity 'emerging pathogens' named entity 'Seoul' named entity 'Bordetella pertussis' named entity 'pathogen' named entity 'Streptococcus pneumoniae' named entity 'coinfection' named entity 'Cary, NC' named entity 'CDC' named entity 'HRV' named entity 'bacterial infection' named entity 'Acute respiratory infections' named entity 'molecular methods' named entity 'viral genome' named entity 'Pavia' named entity 'cDNA' named entity 'bacteria' named entity 'pneumonia' named entity 'H1N1' named entity 'multivariate analysis' named entity 'S. pneumoniae' named entity 'community-acquired pneumonia' named entity 'coinfected' named entity 'epidemics' named entity 'respiratory tract' named entity 'medical history' named entity 'lower respiratory tract infections' named entity 'virulence factors' named entity 'CDC' named entity 'patient records' named entity '2009 pandemic' named entity 'bacteria' named entity 'viruses' named entity '1, 2' named entity 'S. aureus'

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