About: Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012

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About: Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012
Creator	Yang, Yan Li, Jianguo Liu, Chunyan Ren, Lili Shen, Kunling Wang, Jianwei Xiao, Yan Xie, Zhengde Zhang, Jing Qian, Suyun Xu, Baoping
Source	Medline; PMC
abstract	BACKGROUND: Human adenoviruses (HAdV) play a significant role in pediatric respiratory tract infections. To date, over 60 types of HAdV have been identified. Here, HAdV types are characterized in children in the Beijing area with acute lower respiratory tract infections (ALRTIs) and the clinical features and laboratory findings of hospitalized HAdV-infected cases are described. METHODS: Respiratory specimens were collected from pediatric patients with ALRTIs in the emergency department or from those admitted to Beijing Children’s Hospital between March 2007 and December 2012. Infections with common respiratory viruses were determined by PCR or RT-PCR. HAdV positive samples were further typed by PCR and sequencing. RESULTS: Among 3356 patients with ALRTIs, 194 (5.8 %) were found to have HAdV infection. HAdV infection was primarily confined to children (88.35 %) less than 5 years of age. A total of 11 different types of HAdV were detected throughout the study period, with HAdV-B7 (49.0 %) and HAdV-B3 (26.3 %) as the most prevalent types, followed by HAdV-C2 (7.7 %) and HAdVC1 (4.6 %). Newly emerging and re-emergent types or variants, HAdV-B55 (n = 5), HAdV-C57 (n = 3), and HAdV-B14p1 (n = 1), were identified. Results also included the reported first case of co-infection with HAdV-C2 and HAdV-C57. Clinical entities of patients with single HAdV infection (n = 49) were similar to those with mixed HAdV/respiratory syncytial virus (RSV) infections (n = 41). Patients with HAdV-B7 infection had longer duration of fever and higher serum levels of muscle enzymes than HAdV-B3-infected patients. CONCLUSIONS: During the study period, HAdV-B7 and HAdV-B3 were the predominant types identified in pediatric ALRTIs. HAdV-B7 infection tends to have more severe clinical consequences. The presence of newly emerging types or variants and co-infection with different types of HAdV highlights the need for constant and close surveillance of HAdV infection.
has issue date	2015-10-01(xsd:dateTime)
bibo:doi	10.1186/s12879-015-1126-2
bibo:pmid	26429778
has license	cc-by
sha1sum (hex)	c3868e20a756883f97b18c851e9e6df7ad0cb11e
schema:url	https://doi.org/10.1186/s12879-015-1126-2
resource representing a document's title	Adenovirus infection in children with acute lower respiratory tract infections in Beijing, China, 2007 to 2012
has PubMed Central identifier	PMC4591558
has PubMed identifier	26429778
schema:publication	BMC Infect Dis
resource representing a document's body	covid:c3868e20a756883f97b18c851e9e6df7ad0cb11e#body_text
is schema:about of	named entity 'respiratory tract infections' named entity 'cases' named entity 'LOWER RESPIRATORY TRACT INFECTIONS' named entity 'CHINA' named entity 'HERE' named entity 'CHILDREN' named entity 'DATE' named entity 'CLINICAL FEATURES' named entity 'IDENTIFIED' named entity 'BEIJING' named entity 'ADENOVIRUSES' named entity 'HOSPITALIZED' named entity 'ACUTE' named entity 'TYPES' named entity 'AREA' named entity 'PLAY' named entity 'SIGNIFICANT' named entity 'LOWER RESPIRATORY TRACT INFECTIONS' named entity 'ACUTE' named entity 'HUMAN' named entity 'OVER 60' covid:arg/c3868e20a756883f97b18c851e9e6df7ad0cb11e named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'BEIJING' named entity 'CHARACTERIZED' named entity 'DESCRIBED' named entity 'FINDINGS' named entity 'ADENOVIRUS INFECTION' named entity 'BACKGROUND' named entity 'HAVE' named entity 'ROLE' named entity 'CASES' named entity 'CHILDREN' named entity 'LABORATORY' named entity 'PEDIATRIC' named entity 'INFECTED' named entity 'hospitalized' named entity 'respiratory tract infections' named entity 'Beijing' named entity 'acute' named entity 'laboratory' named entity 'respiratory tract infections' named entity 'Beijing' named entity 'Beijing' named entity 'human rhinovirus' named entity 'evolution' named entity 'endemic' named entity 'serum' named entity 'RSV' named entity 'virus' named entity 'HRV' named entity 'gene' named entity 'respiratory tract' named entity 'lung' named entity 'gene' named entity 'Biochemical tests' named entity 'HBDH' named entity 'RSV' named entity 'serum' named entity 'bronchopulmonary dysplasia' named entity 'RSV' named entity 'China' named entity 'Beijing' named entity 'alanine aminotransferase' named entity 'infection rate' named entity 'Chest X-rays' named entity 'throat swab' named entity 'WBC' named entity 'HRV' named entity 'tissue damage' named entity 'infection'

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