About: Virus like particle-based vaccines against emerging infectious disease viruses

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About: Virus like particle-based vaccines against emerging infectious disease viruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Virus like particle-based vaccines against emerging infectious disease viruses
Creator	Deng, Fei Hu, Zhihong Wang, Hualin Wang, Manli Dai, Shiyu Liu, Jinliang
Source	Medline; PMC
abstract	Emerging infectious diseases are major threats to human health. Most severe viral disease outbreaks occur in developing regions where health conditions are poor. With increased international travel and business, the possibility of eventually transmitting infectious viruses between different countries is increasing. The most effective approach in preventing viral diseases is vaccination. However, vaccines are not currently available for numerous viral diseases. Virus-like particles (VLPs) are engineered vaccine candidates that have been studied for decades. VLPs are constructed by viral protein expression in various expression systems that promote the selfassembly of proteins into structures resembling virus particles. VLPs have antigenicity similar to that of the native virus, but are non-infectious as they lack key viral genetic material. VLP vaccines have attracted considerable research interest because they offer several advantages over traditional vaccines. Studies have shown that VLP vaccines can stimulate both humoral and cellular immune responses, which may offer effective antiviral protection. Here we review recent developments with VLP-based vaccines for several highly virulent emerging or re-emerging infectious diseases. The infectious agents discussed include RNA viruses from different virus families, such as the Arenaviridae, Bunyaviridae, Caliciviridae, Coronaviridae, Filoviridae, Flaviviridae, Orthomyxoviridae, Paramyxoviridae, and Togaviridae families.
has issue date	2016-07-11(xsd:dateTime)
bibo:doi	10.1007/s12250-016-3756-y
bibo:pmid	27405928
has license	no-cc
sha1sum (hex)	c3fe4fb2909b5d4ca97c2a19c69bb3ed1102a555
schema:url	https://doi.org/10.1007/s12250-016-3756-y
resource representing a document's title	Virus like particle-based vaccines against emerging infectious disease viruses
has PubMed Central identifier	PMC7090901
has PubMed identifier	27405928
schema:publication	Virol Sin
resource representing a document's body	covid:c3fe4fb2909b5d4ca97c2a19c69bb3ed1102a555#body_text
is schema:about of	named entity 'BASED' named entity 'emerging' named entity 'families' named entity 'highly' named entity 'outbreaks' named entity 'conditions' named entity 'families' named entity 'VLP' named entity 'NATIVE' named entity 'FAMILIES' named entity 'NON-' named entity 'EMERGING INFECTIOUS DISEASES' named entity 'TOGAVIRIDAE' named entity 'PROMOTE' named entity 'APPROACH' named entity 'WHERE' named entity 'REVIEW' named entity 'CURRENTLY' named entity 'INCREASING' named entity 'PROTECTION' named entity 'VLP' named entity 'SEVERE' named entity 'EMERGING OR RE-EMERGING' named entity 'CONSTRUCTED' named entity 'INCLUDE' named entity 'ANTIVIRAL' named entity 'HUMAN HEALTH' named entity 'TRADITIONAL' named entity 'VARIOUS' named entity 'POSSIBILITY OF' named entity 'VACCINES' named entity 'VIRAL DISEASE' named entity 'OFFER' named entity 'ARENAVIRIDAE' named entity 'THREATS' named entity 'DIFFERENT' named entity 'PARTICLE' named entity 'LIKE' named entity 'EXPRESSION' named entity 'HERE' named entity 'AVAILABLE' named entity 'POOR' named entity 'VIRUSES' named entity 'EMERGING INFECTIOUS DISEASE' named entity 'BUNYAVIRIDAE' named entity 'MAJOR' named entity 'FILOVIRIDAE' named entity 'EFFECTIVE' named entity 'OCCUR' named entity 'SYSTEMS' named entity 'ORTHOMYXOVIRIDAE' named entity 'CORONAVIRIDAE' named entity 'DISEASE OUTBREAKS' named entity 'COUNTRIES' named entity 'INFECTIOUS' named entity 'NUMEROUS' named entity 'INFECTIOUS AGENTS' named entity 'BUSINESS' named entity 'LACK' named entity 'CONSIDERABLE' named entity 'STIMULATE' named entity 'SIMILAR' named entity 'GENETIC MATERIAL' named entity 'BUT' named entity 'INTEREST' named entity 'VIRUSLIKE PARTICLES' named entity 'FLAVIVIRIDAE' named entity 'CELLULAR' named entity 'TRANSMITTING' named entity 'HEALTH CONDITIONS' named entity 'REVIEW' named entity 'VACCINE' named entity 'PREVENTING' named entity 'VLPS' named entity 'VIRAL PROTEIN' named entity 'HAVE'

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