About: Pneumonia and wheezing in the first year: An international perspective

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Pneumonia and wheezing in the first year: An international perspective
Creator	Garcia-Marcos, Luis Mallol, Javier Camargos, Paulo Salvador, El Salvador, San Brand, Paul Cepeda, Alfonso Aguirre, Viviana Aldrey, Oscar Alegre, Porto Angel, López-Silvarrey Baeza-Bacab, Manuel Bercedo Sanz, Alberto Bessa, Costa Brazil, ( Brazil, Bianca Brazil, Elaine Bueso, Agustín Calvo, Mario Capriles, Arnaldo Chong, Herberto Coruña, María Cousin, Luis Della, Caroline Dirceu, ) Elix, F Es González, Andr Figueroa, Margarita Fischer, Gilberto Gallardo, Alejandro González-Díaz, Carlos Guill, Francisco Horizonte, Bello Jussara Fernández-Fontes, Maria Libertad, La Luis, ; Martinez-Torres, Antonela Medeiros, Ecio Morales Suárez-Varela, ( P Erez-Fernández, Virginia Pellegrini, Javier Prestes, Emanuel Rocha, Wilson Rosario, Nelson Sanchez-Solis, Manuel Sarinho, Sol, Dirceu Spain, ( Spain, Belinchón Spain, Grima Spain, Hermosa Spain, La Spain, Valencia Sula, Pedro Sánchez-Bahillo, Maria Sánchez-Solís, Manuel Toledano, Lorente Varela, ( Venezuela, ( Visser, Chantal
Source	Medline; PMC
abstract	BACKGROUND: The relationship between pneumonia and recurrent wheezing (RW) and the factors associated to pneumonia in wheezing and non‐wheezing infants have not been compared between affluent and non‐affluent populations. METHODS: The International Study of Wheezing in Infants (EISL) is a large population‐based cross‐sectional study carried out in Latin America (LA) and Europe (EU). We used a validated questionnaire for identifying wheeze in the first year of life. The questionnaire also inquired about pneumonia diagnosis, together with other potentially related factors. Associations between both conditions and between potential risk/protective factors for pneumonia were tested by random‐effects logit model and adjusting for all factors found previously associated to RW in this cohort. RESULTS: Pneumonia and RW were strongly associated to each other in LA and EU (aOR 5.42; 95%CI: 4.87–6.04 and aOR 13.99; 95%CI: 9.61–20.36, respectively). Infant eczema was the most consistent risk factor of pneumonia in both continents, in the whole population and also among wheezers and non‐wheezers (aOR ranging from 1.30; 95%CI: 1.11–1.52 to 2.65; 95%CI: 1.68–4.18); while breast feeding for at least 3 months was the most consistent protective factor (aOR ranging from 0.60; 95%CI: 0.51–0.71 to 0.76; 95%CI: 0.69–0.84). Factors associated to pneumonia were similar between continents among wheezers, but differed considerably among non‐wheezers. CONCLUSION: Pneumonia and RW are associated conditions sharing many risk/protective factors in EU and LA among wheezing infants, but not among non‐wheezing infants. The association between pneumonia and RW could be due to shared pathophysiology or by diagnostic confusion between the two conditions. Pediatr Pulmonol. 2015; 50:1277–1285. © 2015 Wiley Periodicals, Inc.
has issue date	2015-02-09(xsd:dateTime)
bibo:doi	10.1002/ppul.23160
bibo:pmid	25676935
has license	no-cc
sha1sum (hex)	c42205eb60bf526b7cb9e0928b4749eb7c88956b
schema:url	https://doi.org/10.1002/ppul.23160
resource representing a document's title	Pneumonia and wheezing in the first year: An international perspective
has PubMed Central identifier	PMC7167825
has PubMed identifier	25676935
schema:publication	Pediatr Pulmonol
resource representing a document's body	covid:c42205eb60bf526b7cb9e0928b4749eb7c88956b#body_text
is schema:about of	named entity 'Methods' named entity 'Europe' named entity 'eczema' named entity 'Latin America' named entity 'Perspective' named entity 'Wheezing' named entity 'AOR' named entity 'ADJUSTING' named entity 'WHEEZE' named entity 'SHARING' named entity 'ASSOCIATIONS' named entity 'TESTED' named entity 'PNEUMONIA' named entity 'aOR' named entity 'factors' named entity 'breast feeding' named entity 'ranging' named entity 'continents' named entity 'risk' named entity 'life' named entity 'risk factor' named entity 'Europe'

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