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About:
The potential of anti‐infectives and immunomodulators as therapies for asthma and asthma exacerbations
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
New Facet based on Instances of this Class
Attributes
Values
type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
The potential of anti‐infectives and immunomodulators as therapies for asthma and asthma exacerbations
Creator
Khaitov, Musa
Skevaki, |
Moscow, Russia
Edwards, M
Feleszko, |
Jackson, |
Jartti, |
Johnston, |
Khaitov, |
Makrinoti, |
Nikonova, |
Schwarze, |
Sera,
Shilovskiy, |
Walton, |
Source
Medline; PMC
abstract
Asthma is responsible for approximately 25,000 deaths annually in Europe despite available medicines that maintain asthma control and reduce asthma exacerbations. Better treatments are urgently needed for the control of chronic asthma and reduction in asthma exacerbations, the major cause of asthma mortality. Much research spanning >20 years shows a strong association between microorganisms including pathogens in asthma onset, severity and exacerbation, yet with the exception of antibiotics, few treatments are available that specifically target the offending pathogens. Recent insights into the microbiome suggest that modulating commensal organisms within the gut or lung may also be a possible way to treat/prevent asthma. The European Academy of Allergy & Clinical Immunology Task Force on Anti‐infectives in Asthma was initiated to investigate the potential of anti‐infectives and immunomodulators in asthma. This review provides a concise summary of the current literature and aimed to identify and address key questions that concern the use of anti‐infectives and both microbe‐ and host‐based immunomodulators and their feasibility for use in asthma.
has issue date
2017-08-10
(
xsd:dateTime
)
bibo:doi
10.1111/all.13257
bibo:pmid
28722755
has license
no-cc
sha1sum (hex)
c5c4ceb7f72af12592d81b9728ae1a839b7add3b
schema:url
https://doi.org/10.1111/all.13257
resource representing a document's title
The potential of anti‐infectives and immunomodulators as therapies for asthma and asthma exacerbations
has PubMed Central identifier
PMC7159495
has PubMed identifier
28722755
schema:publication
Allergy
resource representing a document's body
covid:c5c4ceb7f72af12592d81b9728ae1a839b7add3b#body_text
is
schema:about
of
named entity 'RESPONSIBLE'
named entity 'microbiology'
named entity 'infection'
named entity 'asthma'
named entity 'pathogen'
named entity 'asthma'
named entity 'asthma'
named entity 'endophenotype'
named entity 'asthma'
named entity 'microbes'
named entity 'antivirals'
named entity 'immune responses'
named entity 'Anti-infectives'
named entity 'chemokines'
named entity 'asthma'
named entity 'clinical trials'
named entity 'adjunctive therapy'
named entity 'TLRs'
named entity 'significant evidence'
named entity 'animal studies'
named entity 'viruses'
named entity 'asthma'
named entity 'Vitamin'
named entity 'inoculated'
named entity 'RSV'
named entity 'probiotic'
named entity 'MMR'
named entity 'preclinical'
named entity 'microbiome'
named entity 'naturally occurring'
named entity 'brincidofovir'
named entity 'secondary endpoints'
named entity 'microbe'
named entity 'asthma'
named entity 'respiratory tract'
named entity 'ARI'
named entity 'nucleoside analogue'
named entity 'neutrophilic'
named entity 'antibiotics'
named entity 'antibody'
named entity 'pathogens'
named entity 'zanamivir'
named entity 'wheezing'
named entity 'secondary prevention'
named entity 'virologically confirmed'
named entity 'pertussis vaccination'
named entity 'agonists'
named entity 'wheezing'
named entity 'Neutralizing antibodies'
named entity 'allergic asthma'
named entity 'Anti-infectives'
named entity 'placebo'
named entity 'wild-type'
named entity 'randomized, double-blind'
named entity 'pathogens'
named entity 'ARIs'
named entity 'microbiome'
named entity 'hepatitis'
named entity 'lymphocyte'
named entity 'asthma'
named entity 'wheezing'
named entity 'asthmatics'
named entity 'cohort study'
named entity 'Antibiotics'
named entity 'meta-analyses'
named entity 'antibiotics'
named entity 'clinical trials'
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