About: Evolution of olfactory disorders in COVID‐19 patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evolution of olfactory disorders in COVID‐19 patients
Creator	Charmillon, Alexandre Nguyen, Gallet, Patrice Bevilacqua, Sibylle Duc, Trung Gorzkowski, Victor Jankowski, Roger Rumeau, Cécile Trung Nguyen, Duc
Source	Medline; PMC
abstract	OBJECTIVES: A high frequency and a strong association of olfactory/gustatory impairment with COVID‐19 were reported. Its spontaneous evolution remains unknown. The aim of this study was to investigate the spontaneous evolution of olfactory disorders in COVID‐19 patients. STUDY DESIGN: Cross‐sectional study METHODS: A total of 229 patients with laboratory‐confirmed COVID‐19 from March 1 through 31, 2020 in our institution were included. Among them, 140 patients (mean age, 38.5 years, 89 women) reported sudden olfactory/gustatory disorders during COVID‐19. All patients were interviewed by phone based on a questionnaire with 16 questions at time of survey. The primary end point was olfactory recovery rate at time of survey. RESULTS: The frequency of patients with olfactory disorders was higher before March 20, 2020 than since (70.3% vs 53.9%, respectively) (p=0.016). At time of survey (26 days of the mean time from anosmia onset), 95.71% reported to start an olfactory recovery. The mean time from olfactory loss onset to recovery onset was 11.6 days. Recovery started between the 4(th) and the 15(th) day after olfactory loss onset in 78.4% of patients. Complete olfactory recovery happened for 51.43% of patients. There was a significant relationship between the complete olfactory recovery and a short time from olfactory loss onset to recovery onset (p=0.0004), absence of nasal obstruction (p=0.023), and absence of sore/dry/tingling feeling in the nose (p=0.007) in COVID‐19 patients. CONCLUSION: Knowledge of spontaneous evolution of olfactory disorders allows reassuring patients and planning therapeutic strategies for persistent olfactory dysfunction after having definitely recovered from COVID‐19.
has issue date	2020-07-02(xsd:dateTime)
bibo:doi	10.1002/lary.28957
bibo:pmid	32617990
has license	no-cc
sha1sum (hex)	c698de0f7eb7363c00f30a2047bf18b34097ef71
schema:url	https://doi.org/10.1002/lary.28957
resource representing a document's title	Evolution of olfactory disorders in COVID‐19 patients
has PubMed Central identifier	PMC7361712
has PubMed identifier	32617990
schema:publication	Laryngoscope
resource representing a document's body	covid:c698de0f7eb7363c00f30a2047bf18b34097ef71#body_text
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