About: Clinical Manifestation and Laboratory Characteristics of SARS-CoV-2 Infection in Pregnant Women

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Manifestation and Laboratory Characteristics of SARS-CoV-2 Infection in Pregnant Women
Creator	Wu, Chunchen Ren, Wei Wu, • Xia, Jianbo Yang, Wenzhong Zhang, Tianzhu Zhao, Yaoyao
Source	Medline; PMC
abstract	The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic has become a major challenge to public health in China and other countries, considering its pathogenicity across all age groups. Pregnancy is a unique physiological condition, and is characterized by altered immunity and elevated hormone levels to actively tolerate the semi-allogeneic fetus, which undergoes a sudden and substantial fluctuation during the immediate postpartum period. Changes in clinical features, laboratory characteristics, and imaging features of pregnant women during the pre-partum and post-partum periods require further elucidation. Here, we retrospectively analyzed the clinical features, laboratory characteristics, and imaging features of eight pregnant cases of SARS-CoV-2 infection during the pre-partum and post-partum periods. Our results showed that four of the eight pregnant women were asymptomatic before delivery but became symptomatic post-partum. Correspondingly, white blood cell (WBC) counts increased and lymphocyte (LYMPH) counts decreased. C-reactive protein (CRP) levels in the serum also increased to a higher level than those in general pregnancy. Therefore, it is imperative to closely monitor laboratory parameters including the WBC count, LYMPH count, and CRP, along with other imaging features in chest CT scans, to promptly prevent, diagnose, and treat a SARS-CoV-2 infection during pregnancy. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12250-020-00227-0) contains supplementary material, which is available to authorized users.
has issue date	2020-04-20(xsd:dateTime)
bibo:doi	10.1007/s12250-020-00227-0
bibo:pmid	32314274
has license	no-cc
sha1sum (hex)	c8237c73a065a32673df9a66f9d0b05ec78426bb
schema:url	https://doi.org/10.1007/s12250-020-00227-0
resource representing a document's title	Clinical Manifestation and Laboratory Characteristics of SARS-CoV-2 Infection in Pregnant Women
has PubMed Central identifier	PMC7167538
has PubMed identifier	32314274
schema:publication	Virol Sin
resource representing a document's body	covid:c8237c73a065a32673df9a66f9d0b05ec78426bb#body_text
is schema:about of	named entity 'laboratory' named entity 'infection' named entity 'retrospectively' named entity 'levels' named entity 'chest' named entity 'Laboratory' named entity 'Characteristics' named entity 'PHYSIOLOGICAL CONDITION' named entity 'CASES' named entity 'EPIDEMIC' named entity 'CRP' named entity 'IMMEDIATE' named entity 'CHARACTERIZED' named entity 'COUNTS' covid:arg/c8237c73a065a32673df9a66f9d0b05ec78426bb named entity 'pathogenicity' named entity 'immunity' named entity 'count' named entity 'Therefore' named entity 'periods' named entity 'levels' named entity 'pregnancy' named entity 'features' named entity 'imaging' named entity 'WBC' named entity 'CT scans' named entity 'pregnancy' named entity 'pregnancy' named entity 'white blood cell' named entity 'SARS-CoV-2' named entity 'China' named entity 'clinical features' named entity 'pathogenicity' named entity 'public health' named entity 'epidemic' named entity 'SARS-CoV-2' named entity 'CRP' named entity 'Pregnant Women' named entity 'ground-glass opacity' named entity 'CT scans' named entity 'shortness of breath' named entity 'D-dimer' named entity 'WBC' named entity 'hormones' named entity 'COVID' named entity 'multiple organ failure' named entity 'ground-glass opacities' named entity 'pathogens' named entity 'pregnant women' named entity 'China' named entity 'infection' named entity 'infection' named entity 'SARS-CoV-2' named entity 'vertical transmission' named entity 'phagocytes' named entity 'post-partum' named entity 'SARS-CoV-2' named entity 'infection' named entity 'SARS-CoV-2' named entity 'lymphocyte' named entity 'infection' named entity 'SARS-CoV-2' named entity 'prepartum' named entity 'Wuhan' named entity 'ground glass opacity' named entity 'infection' named entity 'CRP' named entity 'LYMPH' named entity 'Pregnancy' named entity 'CT scans' named entity 'infection' named entity 'antibiotic treatment' named entity 'National Health Commission' named entity 'high fever' named entity 'SARS-CoV-2'

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