About: Current Progress of Virus-mimicking Nanocarriers for Drug Delivery

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Current Progress of Virus-mimicking Nanocarriers for Drug Delivery
Creator	Liu, Qiushi Somiya, Masaharu Ichi Kuroda, Shun
source	Medline; PMC
abstract	Nanomedicines often involve the use of nanocarriers as a delivery system for drugs or genes for maximizing the therapeutic effect and/or minimizing the adverse effect. From drug administration to therapeutic activity, nanocarriers must evade the host's immune system, specifically and efficiently target and enter the cell, and release their payload into the cell cytoplasm by endosomal escape. These processes constitute the early infection stage of viruses. Viruses are a powerful natural nanomaterial for the efficient delivery of genetic information by sophisticated mechanisms. Over the past two decades, many virus-inspired nanocarriers have been generated to permit successful drug and gene delivery. In this review, we summarize the early infection machineries of viruses, of which the part has so far been utilized for delivery systems. Furthermore, we describe basics and applications of the bio-nanocapsule, which is a hepatitis B virus-mimicking nanoparticle harboring nearly all activities involved in the early infection machineries (i.e., stealth activity, targeting activity, cell entry activity, endosomal escaping activity).
has issue date	2017-10-31(xsd:dateTime)
bibo:doi	10.7150/ntno.21723
bibo:pmid	29188175
has license	cc-by-nc
sha1sum (hex)	c8b0ef630df7327adda9757e8cca4aaac3fe69b3
schema:url	https://doi.org/10.7150/ntno.21723
resource representing a document's title	Current Progress of Virus-mimicking Nanocarriers for Drug Delivery
has PubMed Central identifier	PMC5704007
has PubMed identifier	29188175
schema:publication	Nanotheranostics
resource representing a document's body	covid:c8b0ef630df7327adda9757e8cca4aaac3fe69b3#body_text
is schema:about of	named entity 'CURRENT' named entity 'VIRUSES' named entity 'GENE DELIVERY' named entity 'APPLICATIONS' named entity 'HOST' named entity 'SUCCESSFUL' named entity 'PROCESSES' named entity 'EFFICIENT' named entity '27S' named entity 'DELIVERY SYSTEM' named entity 'HARBORING' named entity 'DRUG' named entity '2C CELL' named entity 'USE OF' named entity 'MECHANISMS' named entity 'administration' named entity 'host' named entity 'payload' named entity 'stealth' named entity 'Viruses' named entity 'involve' named entity 'REVIEW' named entity 'ESCAPE' named entity 'THEIR' named entity 'NEARLY' named entity 'GENETIC INFORMATION' named entity 'THESE' named entity 'PROGRESS' named entity 'IMMUNE SYSTEM' named entity 'CYTOPLASM' named entity 'HAVE' named entity 'DRUGS' named entity 'TARGETING' named entity 'PERMIT' named entity '28I' named entity 'HEPATITIS B VIRUS' named entity 'STAGE' named entity 'THERAPEUTIC EFFECT' named entity 'NANOPARTICLE' named entity 'THE CELL' named entity 'INFECTION' named entity 'INSPIRED' named entity 'NANOMATERIAL' named entity 'DESCRIBE' named entity 'EARLY' named entity 'TARGET' named entity 'DELIVERY' named entity 'ENTRY' named entity 'FAR' named entity 'IS A' named entity 'DRUG DELIVERY' named entity 'RELEASE' named entity 'DRUG ADMINISTRATION' named entity 'A HEPATITIS' named entity 'ACTIVITY' named entity 'VIRUS' named entity 'GENERATED' named entity 'ENTER' named entity 'VIRUS' named entity 'BIO-NANOCAPSULE' named entity 'NATURAL' named entity 'INVOLVED' named entity 'GENES' named entity 'THERAPEUTIC' named entity 'ACTIVITIES' named entity 'ADVERSE EFFECT' named entity 'PAST' named entity 'POWERFUL' named entity 'nanoparticle' named entity 'infection' named entity 'involved' named entity 'therapeutic' named entity 'sophisticated' named entity 'drugs' named entity 'escaping' named entity 'adverse' named entity 'system' named entity 'basics' named entity 'escape'

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