About: Neurological manifestations of COVID-19: available evidences and a new paradigm

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About: Neurological manifestations of COVID-19: available evidences and a new paradigm Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Neurological manifestations of COVID-19: available evidences and a new paradigm
Creator	Khatoon, Fatima Kumar, Vijay Prasad, Kartikay
Source	Medline; PMC
abstract	The recent pandemic outbreak of coronavirus is pathogenic and a highly transmittable viral infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). In this time of ongoing pandemic, many emerging reports suggested that the SARS-CoV-2 has inimical effects on neurological functions, and even causes serious neurological damage. The neurological symptoms associated with COVID-19 include headache, dizziness, depression, anosmia, encephalitis, stroke, epileptic seizures, and Guillain-Barre syndrome along with many others. The involvement of the CNS may be related with poor prognosis and disease worsening. Here, we review the evidence of nervous system involvement and currently known neurological manifestations in COVID-19 infections caused by SARS-CoV-2. We prioritize the 332 human targets of SARS-CoV-2 according to their association with brain-related disease and identified 73 candidate genes. We prioritize these 73 genes according to their spatio-temporal expression in the different regions of brain and also through evolutionary intolerance analysis. The prioritized genes could be considered potential indicators of COVID-19-associated neurological symptoms and thus act as a possible therapeutic target for the prevention and treatment of CNS manifestations associated with COVID-19 patients.
has issue date	2020-08-24(xsd:dateTime)
bibo:doi	10.1007/s13365-020-00895-4
bibo:pmid	32839951
has license	no-cc
sha1sum (hex)	c8e12abcd53c476ff2999587d32273ad5bbab85e
schema:url	https://doi.org/10.1007/s13365-020-00895-4
resource representing a document's title	Neurological manifestations of COVID-19: available evidences and a new paradigm
has PubMed Central identifier	PMC7444681
has PubMed identifier	32839951
schema:publication	J Neurovirol
resource representing a document's body	covid:c8e12abcd53c476ff2999587d32273ad5bbab85e#body_text
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