About: Acquired neuromuscular disorders in critically ill patients: a systematic review

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Acquired neuromuscular disorders in critically ill patients: a systematic review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Acquired neuromuscular disorders in critically ill patients: a systematic review
Creator	Mondor, Henri Carlet, J Cook, D Cook, Jonghe De Jonghe, B De, B De, Service Fonctionnelles, Physiologie-Explorations Lefaucheur, J.-P Outin, H Outin, × Sharshar, T
source	PMC
abstract	Objective: To summarize the prospective clinical studies of neuromuscular abnormalities in intensive care unit (ICU) patients. Study identification and selection: Studies were identified through MEDLINE, EMBASE, references in primary and review articles, personal files, and contact with authors. Through duplicate independent review, we selected prospective cohort studies evaluating ICU-acquired neuromuscular disorders. Data abstraction: In duplicate, independently, we abstracted key data regarding design features, the population, clinical and laboratory diagnostic tests, and clinical outcomes. Results: We identified eight studies that enrolled 242 patients. Inception cohorts varied; some were mechanically ventilated patients for ≥ 5 days, others were based on a diagnosis of sepsis, organ failure, or severe asthma while others were selected on the basis of exposure to muscle relaxants, or because of participation in muscle biochemistry studies. Weakness was systematically assessed in two of the eight studies, concerning patients with severe asthma, with a reported frequency of 36 and 70 %, respectively. Electrophysiologic and histologic abnormalities consisted of both peripheral nerve and muscle involvement and were frequently reported, even in non-selected ICU patients. In a population of patients mechanically ventilated for more than 5 days, electrophysiologic abnormalities were reported in 76 % of cases. Two studies showed a clinically important increase (5 and 9 days, respectively) in duration of mechanical ventilation and a mortality twice as high in patients with critical illness neuromuscular abnormalities, compared to those without. Conclusions: Prospective studies of ICU-acquired neuromuscular abnormalities include a small number of patients with various electrophysiologic findings but insufficiently reported clinical correlations. Evaluation of risk factors for these disorders and studies examining their contribution to weaning difficulties and long-term disability are needed.
has issue date	1998-01-01(xsd:dateTime)
bibo:doi	10.1007/s001340050757
bibo:pmid	9885875
has license	no-cc
sha1sum (hex)	c9423249e37051fad0a9cf9e6dae6274cb6511c9
schema:url	https://doi.org/10.1007/s001340050757
resource representing a document's title	Acquired neuromuscular disorders in critically ill patients: a systematic review
has PubMed Central identifier	PMC7094970
has PubMed identifier	9885875
schema:publication	Intensive Care Med
resource representing a document's body	covid:c9423249e37051fad0a9cf9e6dae6274cb6511c9#body_text
is schema:about of	named entity 'critical illness' named entity 'severe' named entity 'neuromuscular system' named entity 'systematic review' named entity 'DESCRIBED' named entity 'WOMAN' named entity 'WEAKNESS' named entity 'CRITICAL ILLNESS' named entity 'ASTHMA' named entity 'patients' named entity 'published' named entity 'hydrocortisone' named entity 'patients' named entity 'mechanical ventilation' named entity 'polyneuropathy' named entity 'case report' named entity 'systematic review' named entity 'ICU' named entity 'confounding' named entity 'muscle biopsies' named entity 'EMBASE' named entity 'clinical outcome' named entity 'immunotherapy' named entity 'histologic' named entity 'ICU' named entity 'MOF' named entity 'prospective studies' named entity '19, 20' named entity 'organ' named entity 'risk factors' named entity 'ICU' named entity 'hypophosphatemia' named entity 'case series' named entity 'muscle fibers' named entity 'aminoglycosides' named entity 'central nervous' named entity 'critical illness' named entity 'sepsis' named entity 'myopathic' named entity 'muscle' named entity 'neuromuscular blockers' named entity 'asthma' named entity 'polyneuropathy' named entity 'cohort studies' named entity 'EMBASE' named entity 'non-depolarizing' named entity 'diabetes' named entity 'proteolysis' named entity 'clinical sign' named entity 'cohort studies' named entity 'electrophysiologic' named entity 'clinical evaluation' named entity 'muscle disease' named entity 'data abstraction' named entity 'critical illness' named entity 'malignancy' named entity 'histologic' named entity 'follow-up' named entity 'ICU' named entity 'corticosteroids' named entity 'clinical studies' named entity 'muscle fiber' named entity 'muscle' named entity 'antibiotics' named entity 'muscle relaxants' named entity 'corticosteroids' named entity 'electrophysiologic' named entity 'intensive care unit' named entity 'ICU' named entity 'selection bias'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software