About: Production and characterization of anti-peptide monoclonal antibodies with specificity for staphylococcal enterotoxins A and B

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About: Production and characterization of anti-peptide monoclonal antibodies with specificity for staphylococcal enterotoxins A and B Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Production and characterization of anti-peptide monoclonal antibodies with specificity for staphylococcal enterotoxins A and B
Creator	Bhatti"'", A Micusanb, V
Source	Elsevier; Medline; PMC
abstract	Abstract A synthetic peptide containing selected epitopes from staphylococcal enterotoxin A (SEA) and enterotoxin B (SEB) was used to produce monoclonal antibodies (Mabs) to respective enterotoxins in a single fusion procedure. The peptide inhibited the reaction of polyclonal anti-SEA or anti-SEB antisera with their homologous enterotoxin, thus showing that the chosen epitopes are part of the antibody-inducing enterotoxin sequences. Two Mabs, Mab-A and Mab-B, reacted with both the peptide and with either SEA or SEB. Used in a double antibody sandwich ELISA, the Mabs were able to quantitate the native SEA or SEB toxins at nanogram levels.
has issue date	1999-03-31(xsd:dateTime)
bibo:doi	10.1016/s0167-7012(98)00110-9
bibo:pmid	10192046
has license	els-covid
sha1sum (hex)	c9ea8a52407be6f9f150a498aa96106af051b395
schema:url	https://doi.org/10.1016/s0167-7012%2898%2900110-9
resource representing a document's title	Production and characterization of anti-peptide monoclonal antibodies with specificity for staphylococcal enterotoxins A and B
has PubMed Central identifier	PMC7133826
has PubMed identifier	10192046
schema:publication	Journal of Microbiological Methods
resource representing a document's body	covid:c9ea8a52407be6f9f150a498aa96106af051b395#body_text
is schema:about of	named entity 'NATIVE' named entity 'FUSION PROCEDURE' named entity 'PART OF' named entity 'INHIBITED' named entity 'TO PRODUCE' named entity 'RIGHTS' named entity 'EPITOPES' named entity 'HOMOLOGOUS' named entity 'MONOCLONAL ANTIBODIES' named entity 'REACTION' named entity 'MAB' named entity 'single' named entity 'peptide' named entity 'sequences' named entity 'epitopes' named entity 'antibody' named entity 'enterotoxins' named entity 'reacted' named entity 'enterotoxin' named entity 'CHARACTERIZATION' named entity 'PEPT' named entity 'SEB' named entity 'METHODS' covid:arg/c9ea8a52407be6f9f150a498aa96106af051b395 named entity 'ENTEROTOXINS' named entity 'DOUBLE' named entity 'NANOGRAM' named entity 'ENTEROTOXINS' named entity 'ENTEROTOXIN B' named entity 'LEVELS' named entity 'SELECTED' named entity 'MONOCLONAL ANTIBODIES' named entity 'CONTAINING' named entity 'USED' named entity 'SYNTHETIC PEPTIDE' named entity 'SINGLE' named entity 'SEQUENCES' named entity 'PRODUCTION' named entity 'SPECIFICITY' named entity 'TOXINS' named entity 'THEIR' named entity 'STAPHYLOCOCCAL ENTEROTOXIN A' named entity 'CHOSEN' named entity 'ANTIBODY' named entity 'POLYCLONAL' named entity 'INDUCING' named entity 'EITHER' named entity 'SEA' named entity 'SCIENCE' named entity 'ANTISERA' named entity 'PEPTIDE' named entity 'ENTEROTOXIN' named entity 'SANDWICH ELISA' named entity 'Mabs' named entity 'enterotoxin' named entity 'nanogram' named entity 'All rights reserved' named entity 'homologous' named entity 'quantitate' named entity 'enterotoxin' named entity 'Mabs' named entity 'synthetic peptide' named entity 'enterotoxin' named entity 'homologous' named entity 'toxins' named entity 'antisera' named entity 'regression analysis' named entity 'IgG' named entity 'absorbance' named entity 'IgG' named entity 'titer' named entity 'mice' named entity 'SED' named entity 'enterotoxins' named entity 'glycine' named entity 'C-terminal' named entity 'Protein' named entity 'peptide' named entity 'peptide' named entity 'intraperitoneally'

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