About: Asthma in COVID-19: An extra chain fitting around the neck?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Asthma in COVID-19: An extra chain fitting around the neck? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Asthma in COVID-19: An extra chain fitting around the neck?
Creator	Duchesne, Juan Hussein, Mohammad Kandil, Emad Omar, Mahmoud Toraih, Eman Attia, Abdallah Kandil, Youssef, Mohanad Houghton, August Aniemeka, Nedum Burley, Nicholas Roos, Jackson Shama, Mohamed Zhang, Allen
Source	MedRxiv
abstract	Introduction The novel coronavirus disease 2019 (COVID-19) has rapidly spread across the globe, overwhelming healthcare systems and depleting resources. The infection has a wide spectrum of presentations, and pre-existing comorbidities have been found to have a dramatic effect on the disease course and prognosis. We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients. Methods We conducted a multi-center retrospective study of positively confirmed COVID-19 patients from multiple hospitals in Louisiana. Demographics, medical history, comorbidities, clinical presentation, daily laboratory values, complications, and outcomes data were collected and analyzed. The primary outcome of interest was in-hospital mortality. Secondary outcomes were Intensive Care Unit (ICU) admission, risk of intubation, duration of mechanical ventilation, and length of hospital stay. Results A total of 502 COVID-19 patients (72 asthma and 430 non-asthma cohorts) were included in the study. The frequency of asthma in hospitalized cohorts was 14.3%, higher than the national prevalence of asthma (7.7%). Univariate analysis revealed that asthma patients were more likely to be obese (75% vs 54.2%, p=0.001), with higher frequency of intubation (40.3% vs 27.8%, p = 0.036), and required longer duration of hospitalization (15.1{+/-}12.5 vs 11.5{+/-}10.6, p=0.015). After adjustment, multivariable analysis showed that asthmatic patients were not associated with higher risk of ICU admission (OR=1.81, 95%CI=0.98-3.09, p=0.06), endotracheal intubation (OR=1.77, 95%CI=0.99-3.04, p=0.06) or complications (OR=1.37, 95%CI=0.82-2.31, p=0.23). Asthmatic patients were not associated with higher odds of prolonged hospital length of stay (OR=1.48, 95%CI=0.82-2.66, p=0.20) or with the duration of ICU stay (OR=0.76, 95%CI=0.28-2.02, p=0.58). Kaplan-Meier curve showed no significant difference in overall survival of the two groups (p=0.65). Conclusion Despite the increased prevalence of hospitalization in asthmatic COVID-19 patients compared to the general population, after adjustment for other variables, it was neither associated with increased severity nor worse outcomes.
has issue date	2020-07-15(xsd:dateTime)
bibo:doi	10.1101/2020.07.13.20153130
has license	medrxiv
sha1sum (hex)	ca485a95e548643d62c8720b214fccb6ded0ff16
schema:url	https://doi.org/10.1101/2020.07.13.20153130
resource representing a document's title	Asthma in COVID-19: An extra chain fitting around the neck?
resource representing a document's body	covid:ca485a95e548643d62c8720b214fccb6ded0ff16#body_text
is schema:about of	named entity 'presentations' named entity 'prognosis' named entity 'OUTCOMES' named entity 'PROGNOSIS' named entity 'HAVE' named entity 'DISEASE PROGRESSION' named entity 'COVID-19' named entity 'RESOURCES' named entity 'CORONAVIRUS DISEASE 2019' named entity 'WIDE' named entity 'depleting resources' named entity 'disease' named entity 'rapidly' named entity 'COVID-19' named entity 'depleting resources' named entity 'Asthma' named entity 'mechanical ventilation' named entity 'preprint' named entity 'TMPRSS2' named entity 'preprint' named entity 'comorbidities' named entity 'goodness-of-fit' named entity 'asthmatic' named entity 'asthma' named entity 'peer review' named entity 'preprint' named entity 'sepsis' named entity 'Organ Failure' named entity 'COVID-19' named entity 'chronic lung disease' named entity 'widely reported' named entity 'high-risk' named entity 'asthmatic' named entity 'false reporting' named entity 'clinical presentation' named entity 'Kidney Function' named entity 'patient outcomes' named entity 'COVID-19 pandemic' named entity 'preprint' named entity 'risk assessment' named entity 'preprint' named entity 'asthma' named entity 'obese' named entity 'COVID' named entity 'body mass index' named entity 'blood urea nitrogen' named entity 'asthma' named entity 'blood pressure' named entity 'asthmatic' named entity 'endotracheal intubation' named entity 'comorbidities' named entity 'systolic blood pressure' named entity 'COVID-19' named entity 'healthcare systems' named entity 'acute kidney injury' named entity 'Centers for Disease Control and Prevention' named entity 'oxygen' named entity 'diabetes' named entity 'bronchial asthma' named entity 'coronavirus' named entity 'Obesity' named entity 'dramatic impact' named entity 'qSOFA' named entity 'preprint' named entity 'higher risk' named entity 'comorbid conditions' named entity 'asthma' named entity 'lymphocyte' named entity 'asthma' named entity 'bicarbonate' named entity 'clinical outcomes' named entity 'mmol/L'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software