About: Effectiveness of the 2010–2011 seasonal influenza vaccine in preventing confirmed influenza hospitalizations in adults: A case

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About: Effectiveness of the 2010–2011 seasonal influenza vaccine in preventing confirmed influenza hospitalizations in adults: A case–case comparison, case-control study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effectiveness of the 2010–2011 seasonal influenza vaccine in preventing confirmed influenza hospitalizations in adults: A case–case comparison, case-control study
Creator	Arnedo-Pena, A Belenguer-Varea, A Carratalá-Munuera, C Díez-Domingo, J Gil-Guillén, V Hernández, Miguel Juan, San Micó-Esparza, J Puig-Barberà, J Pérez-Vilar, S Ruiz-García, M Schwarz-Chavarri, H
Source	Elsevier; Medline; PMC
abstract	Abstract Introduction We estimated influenza vaccine effectiveness (IVE) to prevent laboratory-confirmed influenza-related hospitalizations in patients 18 years old or older during the 2010–2011 influenza season. Methods We conducted a prospective case-control study in five hospitals, in Valencia, Spain. Study subjects were consecutive emergency hospitalizations for predefined conditions associated with an influenza-like illness episode <8 days before admission. Patients were considered immunized if vaccinated ≥14 days before influenza-like illness onset. Cases were those with a real time reverse transcriptase polymerase chain reaction (RT-PCR) positive for influenza and controls were RT-PCR positive for other respiratory viruses. Adjusted IVE was estimated as 100×(1−adjusted odds ratio). To account for indication bias we computed adjusted IVE for respiratory syncytial virus related hospitalizations. Results Of 826 eligible hospitalized patients, 102 (12%) were influenza positive and considered cases, and 116 (14%) were positive for other respiratory viruses and considered controls. Adjusted IVE was 54% (95% confidence interval, 11–76%). By subgroup, adjusted IVE was 53% (4–77%) for those with high-risk conditions, 59% (16–79%) for those ≥60 years of age, and, 54% (4–79%) for those ≥60 years of age with high-risk conditions. No influenza vaccine effect was observed against respiratory syncytial virus related hospitalization. Conclusion Influenza vaccination was associated with a significant reduction on the risk of confirmed influenza hospitalization, irrespective of age and high-risk conditions.
has issue date	2012-08-24(xsd:dateTime)
bibo:doi	10.1016/j.vaccine.2012.07.006
bibo:pmid	22819720
has license	els-covid
sha1sum (hex)	ca5b0374e1226b4e98aa7c06e5f732b1bd7a2659
schema:url	https://doi.org/10.1016/j.vaccine.2012.07.006
resource representing a document's title	Effectiveness of the 2010–2011 seasonal influenza vaccine in preventing confirmed influenza hospitalizations in adults: A case–case comparison, case-control study
has PubMed Central identifier	PMC7115682
has PubMed identifier	22819720
schema:publication	Vaccine
resource representing a document's body	covid:ca5b0374e1226b4e98aa7c06e5f732b1bd7a2659#body_text
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