About: Utility of lateral flow tests in SARS-CoV-2 infection monitorization

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About: Utility of lateral flow tests in SARS-CoV-2 infection monitorization Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Utility of lateral flow tests in SARS-CoV-2 infection monitorization
Creator	Castillo, Del González, Juan Barreiro, Pablo Canora, Jesús David, Píriz De Casasola, García Española De Quimioterapia, Revista Gil, Ruth Gonzalo, Lebrato González, Candel Hernández, Alba Javier, Francisco Javier, Roa Jesús, Prieto Manuel, José Marcos, García Martín, Barba Martínez, Marco Montero, San-Román Original, Gaviria Ortega, Justo Prados, Fernando Raquel, Anselmi Saavedra, Fragiel Virumbrales, Jiménez Zapatero, Antonio
source	Medline; PMC
abstract	INTRODUCTION: The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. Serology testing allows for the detection of asymptomatic infections and 19-COVID cases once the virus has been cleared. We analyzed the usefulness of the SARS-CoV-2 rapid test of Autobio and tried to correlate its pattern with the severity of COVID19 infection. MATERIAL AND METHODS: We analyzed the accuracy and clinical usefulness of a point-of-care IgM and/or IgG test for SARS-CoV-2 in 35 COVID-19 patients [12 (34.3%) mild-moderate and 23 (65.7%) severe-critical] admitted to a field hospital in Madrid, as well as in 5 controls. RESULTS: The mean time from the first day of symptoms to the antibody test was 28 days (SD: 8.7), similar according to the severity of the disease. All patients with SARS-CoV-2 PCR+ showed the corresponding IgG positivity, while these results were negative in all control individuals. A total of 26 (74%) cases also presented with positive IgM, 19 (83%) were severe-critical cases and 7 (58%) were mild-moderate cases. The IgM response lasted longer in the severe critical cases (mean: 29.7 days; SD: 8.4) compared to the moderate cases (mean: 21.2 days; SD: 2.0). CONCLUSIONS: Rapid serology tests are useful for the diagnosis of patients with COVID-19 (mainly IgG detection) and may also be correlated with the severity of the infection (based on IgM detection).
has issue date	2020-06-04(xsd:dateTime)
bibo:doi	10.37201/req/052.2020
bibo:pmid	32492991
has license	cc-by-nc
sha1sum (hex)	ca7d6838d88773be483537c937804979f3a026ba
schema:url	https://doi.org/10.37201/req/052.2020
resource representing a document's title	Utility of lateral flow tests in SARS-CoV-2 infection monitorization
has PubMed Central identifier	PMC7374028
has PubMed identifier	32492991
schema:publication	Rev Esp Quimioter
resource representing a document's body	covid:ca7d6838d88773be483537c937804979f3a026ba#body_text
is schema:about of	named entity 'SARS-CoV-2' named entity 'virus' named entity 'infección' named entity 'COVID-19' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'CT Scan' named entity 'clinical research ethics' named entity 'blood oxygen saturation' named entity 'seroconversion' named entity 'virus' named entity 'antibody' named entity 'RT-PCR' named entity 'septic shock' named entity 'acute respiratory distress syndrome' named entity 'public health' named entity 'infection' named entity 'Spain' named entity 'SARS-CoV-2' named entity 'IgM' named entity 'humoral responses' named entity 'gold standard' named entity 'conjugation' named entity 'antigen' named entity 'infection' named entity 'seroconversion' named entity 'vomiting' named entity 'B-cell' named entity 'immunoglobulin' named entity 'primary care' named entity 'COVID-19' named entity 'nausea' named entity 'IgG' named entity 'thrombosis' named entity 'Serology' named entity 'IgM' named entity 'IgG' named entity 'ADE' named entity 'inflammation' named entity 'immune response' named entity 'rapid tests' named entity 'virus' named entity 'IgM' named entity 'viral infections' named entity 'sample size' named entity 'SARS-CoV-2' named entity 'multiorgan dysfunction' named entity 'Fc region' named entity 'IgG' named entity '28 days' named entity 'IgM' named entity 'IgM' named entity 'SARS-CoV-2' named entity 'infection' named entity 'COVID' named entity 'infection'

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