About: Technologies and Standardization in Research on Extracellular Vesicles

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Technologies and Standardization in Research on Extracellular Vesicles
Creator	Ivanov, Alexander Alli, Sarath Amiji, Mansoor Gandham, Srujan Milane, Lara Nocera, Angela Su, Xianyi Wood, Jacqueline Zimmerman, Alan
Source	Elsevier; Medline; PMC
abstract	Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various cells into physiological fluids. EV-mediated transfer of biomolecules is a critical component of a variety of physiological and pathological processes. Potential applications of EVs in novel diagnostic and therapeutic strategies have brought increasing attention. However, EV research remains highly challenging due to the inherently complex biogenesis of EVs and their vast heterogeneity in size, composition, and origin. There is a need for the establishment of standardized methods that address EV heterogeneity and sources of pre-analytical and analytical variability in EV studies. Here, we review technologies developed for EV isolation and characterization and discuss paths toward standardization in EV research.
has issue date	2020-06-18(xsd:dateTime)
bibo:doi	10.1016/j.tibtech.2020.05.012
bibo:pmid	32564882
has license	no-cc
sha1sum (hex)	cb90f264ffd2865b53ae2680fad5db1b975d5077
schema:url	https://doi.org/10.1016/j.tibtech.2020.05.012
resource representing a document's title	Technologies and Standardization in Research on Extracellular Vesicles
has PubMed Central identifier	PMC7302792
has PubMed identifier	32564882
schema:publication	Trends Biotechnol
resource representing a document's body	covid:cb90f264ffd2865b53ae2680fad5db1b975d5077#body_text
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