About: Aptamers against pathogenic microorganisms

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Aptamers against pathogenic microorganisms
Creator	Altman, Sidney Davydova, Anna Pyshnyi, Dmitrii Venyaminova, Alya Vlassov, Valentin Vorobjeva, Maria
Source	Medline; PMC
abstract	An important current issue of modern molecular medicine and biotechnology is the search for new approaches to early diagnostic assays and adequate therapy of infectious diseases. One of the promising solutions to this problem might be a development of nucleic acid aptamers capable of interacting specifically with bacteria, protozoa, and viruses. Such aptamers can be used for the specific recognition of infectious agents as well as for blocking of their functions. The present review summarizes various modern SELEX techniques used in this field, and of several currently identified aptamers against viral particles and unicellular organisms, and their applications. The prospects of applying nucleic acid aptamers for the development of novel detection systems and antibacterial and antiviral drugs are discussed.
has issue date	2016-11-01(xsd:dateTime)
bibo:doi	10.3109/1040841x.2015.1070115
bibo:pmid	26258445
has license	no-cc
sha1sum (hex)	cd492bb5d19539c9666aaa080e941f1e6e35f923
schema:url	https://doi.org/10.3109/1040841x.2015.1070115
resource representing a document's title	Aptamers against pathogenic microorganisms
has PubMed Central identifier	PMC5022137
has PubMed identifier	26258445
schema:publication	Crit Rev Microbiol
resource representing a document's body	covid:cd492bb5d19539c9666aaa080e941f1e6e35f923#body_text
is schema:about of	named entity 'INTERACTING' named entity 'DEVELOPMENT' named entity 'INFECTIOUS AGENTS' named entity 'CURRENT' named entity 'BLOCKING' named entity 'IDENTIFIED' named entity 'THEIR' named entity 'IMPORTANT' named entity 'VARIOUS' named entity 'MIGHT BE' named entity 'APPROACHES' named entity 'APPLICATIONS' named entity 'DETECTION' named entity 'BIOTECHNOLOGY' named entity 'SELEX' named entity 'BACTERIA' named entity 'ONE OF' named entity 'EARLY' named entity 'NOVEL' named entity 'PATHOGENIC' named entity 'APPLYING' named entity 'USED' named entity 'APTAMERS' named entity 'THERAPY' named entity 'PROBLEM' named entity 'VIRAL PARTICLES' named entity 'DIAGNOSTIC' named entity 'MICROORGANISMS' named entity 'APTAMERS' named entity 'MOLECULAR MEDICINE' named entity 'RECOGNITION' named entity 'INFECTIOUS DISEASES' named entity 'ADEQUATE' named entity 'NUCLEIC ACID APTAMERS' named entity 'CAPABLE' named entity 'FIELD' named entity 'UNICELLULAR ORGANISMS' named entity 'ANTIVIRAL DRUGS' named entity 'ISSUE' named entity 'TECHNIQUES' named entity 'SYSTEMS' named entity 'CURRENTLY' named entity 'PRESENT' named entity 'REVIEW' named entity 'FUNCTIONS' named entity 'ANTIBACTERIAL' named entity 'PROTOZOA' named entity 'NEW' named entity 'SEARCH' named entity 'SPECIFIC' named entity 'SOLUTIONS' named entity 'VIRUSES' covid:arg/cd492bb5d19539c9666aaa080e941f1e6e35f923 named entity 'nucleic acid' named entity 'infectious agents' named entity 'diagnostic assays' named entity 'aptamers' named entity 'SELEX' named entity 'pathogenic microorganisms' named entity 'biosensor' named entity 'protein targets' named entity 'virulent' named entity 'Leishmania infantum' named entity 'avian influenza' named entity 'covalently' named entity 'aptamers' named entity 'diagnostic tools' named entity 'survival rate' named entity 'electrochemical' named entity 'survival rate' named entity 'CD4' named entity 'Trypanosoma brucei' named entity 'life-threatening diseases' named entity 'aptamer' named entity 'molecule' named entity 'SELEX'

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