About: CXCL10/IP-10 in Infectious Diseases Pathogenesis and Potential Therapeutic Implications

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	CXCL10/IP-10 in Infectious Diseases Pathogenesis and Potential Therapeutic Implications
Creator	Guo, Shanchun Jain, Vidhan Liu, Mingli Singh, Neeru Hibbert, Jacqueline Stiles, Jonathan Wilson, Nana
source	Elsevier; Medline; PMC
abstract	C-X-C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family. CXCL10 binds CXCR3 receptor to induce chemotaxis, apoptosis, cell growth and angiostasis. Alterations in CXCL10 expression levels have been associated with inflammatory diseases including infectious diseases, immune dysfunction and tumor development. CXCL10 is also recognized as a biomarker that predicts severity of various diseases. A review of the emerging role of CXCL10 in pathogenesis of infectious diseases revealed diverse roles of CXCL10 in disease initiation and progression. The potential utilization of CXCL10 as a therapeutic target for infectious diseases is discussed.
has issue date	2011-07-01(xsd:dateTime)
bibo:doi	10.1016/j.cytogfr.2011.06.001
bibo:pmid	21802343
has license	green-oa
sha1sum (hex)	cd78c92eee1fc0049e85e39229c8eca5b9334415
schema:url	https://doi.org/10.1016/j.cytogfr.2011.06.001
resource representing a document's title	CXCL10/IP-10 in Infectious Diseases Pathogenesis and Potential Therapeutic Implications
has PubMed Central identifier	PMC3203691
has PubMed identifier	21802343
schema:publication	Cytokine & Growth Factor Reviews
resource representing a document's body	covid:cd78c92eee1fc0049e85e39229c8eca5b9334415#body_text
is schema:about of	named entity 'interferon' named entity 'kDa' named entity 'chemokine' named entity 'Therapeutic' named entity 'PATHOGENESIS' named entity 'INDUCED' named entity '2C CELL' named entity 'SMALL-INDUCIBLE CYTOKINE B10' named entity '10%' named entity 'POTENTIAL' named entity 'PROGRESSION' named entity 'CXCR3 RECEPTOR' named entity 'TUMOR' named entity 'THERAPEUTIC TARGET' named entity 'CXCL10' named entity 'DISEASES' named entity 'SEVERITY' named entity 'BINDS' named entity 'CELL GROWTH' named entity 'INFLAMMATORY DISEASES' named entity 'CYTOKINE ' named entity 'INTERFERON ' named entity 'ROLES' named entity 'APOPTOSIS' named entity 'FAMILY' named entity 'PROTEIN ' named entity 'BIOMARKER' named entity 'INITIATION' named entity 'DEVELOPMENT' named entity 'INFECTIOUS DISEASES' named entity 'BELONGING' named entity 'C-X-C MOTIF CHEMOKINE 10' named entity 'REVEALED' named entity 'CHEMOTAXIS' named entity 'ASSOCIATED WITH' named entity 'IS A' named entity 'ALTERATIONS' named entity 'HAVE' named entity 'CXCL10' named entity 'POTENTIAL' named entity 'INFECTIOUS DISEASES' named entity 'DIVERSE' named entity 'UTILIZATION' named entity 'DISEASE' named entity 'VARIOUS' named entity 'INCLUDING' named entity 'ROLE' named entity 'INDUCE' named entity 'REVIEW OF' named entity 'IMMUNE DYSFUNCTION' named entity 'KDA' named entity 'EXPRESSION' named entity 'KNOWN' named entity 'CXC CHEMOKINE' named entity 'PATHOGENESIS' named entity 'THERAPEUTIC' named entity 'LEVELS' named entity 'inflammatory diseases' named entity 'infectious diseases' named entity 'motif' named entity 'B10' named entity 'protein' named entity 'infectious diseases' named entity 'chemokine' named entity 'CXCL10' named entity 'kDa' named entity 'cytokine' named entity 'CXCL10' named entity 'tumor' named entity 'CXC chemokine family' named entity 'CXCL10' named entity 'interferon γ' named entity 'biomarker' named entity 'expression levels' named entity 'cytokine'

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