About: Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus

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About: Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus
Creator	Ren, Xiaofeng Yin, Jiechao Sui, Xiuwen
Source	Elsevier; Medline; PMC
abstract	Abstract Diammonium glycyrrhizin (DG), a salt from glycyrrhizinate (GL) that is a major active component of licorice root extract with various pharmacological activities was investigated for its inhibitory effect on pseudorabies virus (PrV) infection. In parallel, lithium chloride (LiCl), a chemical reagent with potential antiviral activity was compared with DG for their inhibitory ability against PrV infection in vitro. Virus plaque-reduction assays, PCR and RT-PCR analysis indicated that both drugs inhibited cell infection by PrV. Moreover, addition of the drugs resulted in fewer apoptotic cells during PrV infection.
has issue date	2010-02-28(xsd:dateTime)
bibo:doi	10.1016/j.antiviral.2009.10.014
bibo:pmid	19879899
has license	els-covid
sha1sum (hex)	cee0724d4b1544eda1581f96962694ecd1f0125b
schema:url	https://doi.org/10.1016/j.antiviral.2009.10.014
resource representing a document's title	Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus
has PubMed Central identifier	PMC7114117
has PubMed identifier	19879899
schema:publication	Antiviral Research
resource representing a document's body	covid:cee0724d4b1544eda1581f96962694ecd1f0125b#body_text
is schema:about of	named entity 'ADDITION' named entity 'COMPONENT' named entity 'GLYCYRRHIZIN' named entity 'PARALLEL' named entity 'ABILITY' named entity 'INDICATED' named entity 'CHEMICAL REAGENT' named entity 'RT-PCR' named entity 'ANTIVIRAL ACTIVITY' named entity 'PCR ANALYSIS' named entity 'COMPARED' named entity 'PHARMACOLOGICAL' named entity 'VIRUS' named entity 'REDUCTION' named entity 'A MAJOR' named entity 'CELLS' named entity 'POTENTIAL' named entity 'INHIBITED' named entity 'IN VITRO' named entity 'PRV' named entity 'GLYCYRRHIZINATE' named entity 'IS A' named entity 'LICORICE ROOT EXTRACT' named entity 'ACTIVITIES' named entity 'PLAQUE' named entity 'THEIR' covid:arg/cee0724d4b1544eda1581f96962694ecd1f0125b named entity 'VARIOUS' named entity 'ITS' named entity 'CELL' named entity 'PCR' named entity 'DRUGS' named entity 'PSEUDORABIES VIRUS' named entity 'HERPESVIRUS' named entity 'EFFECT' named entity 'LITHIUM CHLORIDE' named entity 'ANTIVIRAL' named entity 'LITHIUM CHLORIDE' named entity 'INHIBITORY' named entity 'APOPTOTIC' named entity 'INVESTIGATED' named entity 'INFECTION' named entity 'INHIBITORY EFFECT' named entity 'SALT' named entity 'ON CELL' named entity 'ACTIVE' named entity 'PSEUDORABIES' named entity 'INFECTION' named entity 'DIAMMONIUM GLYCYRRHIZINATE' named entity 'Virus' named entity 'infection' named entity 'PCR' named entity 'pharmacological activities' named entity 'lithium chloride' named entity 'herpesvirus' named entity 'infection' named entity 'host range' named entity 'gout' named entity 'cell morphology' named entity 'LiCl' named entity 'staining' named entity 'virus' named entity 'salt' named entity 'DMEM' named entity 'gene' named entity 'viruses' named entity 'treatment group' named entity 'LiCl' named entity 'apoptosis' named entity 'infectivity' named entity 'gene' named entity 'infection' named entity 'Japan' named entity 'anti-apoptotic' named entity 'hpi' named entity 'viruses' named entity 'Bright's disease' named entity 'JNK' named entity 'binding site'

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