About: Viral Respiratory Tract Infections in Allogeneic Hematopoietic Stem Cell Transplantation Recipients in the Era of Molecular Testing

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About: Viral Respiratory Tract Infections in Allogeneic Hematopoietic Stem Cell Transplantation Recipients in the Era of Molecular Testing Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral Respiratory Tract Infections in Allogeneic Hematopoietic Stem Cell Transplantation Recipients in the Era of Molecular Testing
Creator	Ritchie, David Slavin, Monica Sullivan, Sheena Teh, Benjamin Leung, Vivian Sim, Starling
Source	Elsevier; Medline; PMC
abstract	Viral respiratory tract infection (vRTI) is a significant cause of morbidity and mortality in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). This study aimed to assess the epidemiologic characteristics, risk factors, and outcomes of vRTI occurring in the period from conditioning to 100 days after allo-HSCT in the era of molecular testing. This study was a retrospective record review of patients who underwent allo-HSCT at Royal Melbourne Hospital between January 2010 and December 2015. Symptomatic patients were tested using respiratory multiplex polymerase chain reaction (PCR). Logistic regression and Kaplan-Meier analysis were used to identify risk factors for vRTI and the risk of death or intensive care unit (ICU) admission, respectively. A total of 382 patients were reviewed, and 65 episodes of vRTI were identified in 56 patients (14.7%). Rhinovirus accounted for the majority of infections (69.2%). The majority of episodes presented initially with upper respiratory tract infection (58.5%), with 28.9% of them progressing to lower respiratory tract infection. Eleven episodes (16.9%) were associated with ICU admission. There were no deaths directly due to vRTI. Previous autologous HSCT was associated with an increased risk of vRTI (odds ratio, 2.1; 95% confidence interval, 1.0 to 4.1). The risks of death (P = .47) or ICU admission (P = .65) were not significantly different by vRTI status. vRTI is common in the first 100 days after allo-HSCT and is associated with ICU admission.
has issue date	2018-03-09(xsd:dateTime)
bibo:doi	10.1016/j.bbmt.2018.03.004
bibo:pmid	29530766
has license	no-cc
sha1sum (hex)	cfe6eb6106cace67bbc87df28776c5b0e3692ff6
schema:url	https://doi.org/10.1016/j.bbmt.2018.03.004
resource representing a document's title	Viral Respiratory Tract Infections in Allogeneic Hematopoietic Stem Cell Transplantation Recipients in the Era of Molecular Testing
has PubMed Central identifier	PMC7110577
has PubMed identifier	29530766
schema:publication	Biol Blood Marrow Transplant
resource representing a document's body	covid:cfe6eb6106cace67bbc87df28776c5b0e3692ff6#body_text
is schema:about of	named entity 'total' named entity 'Logistic regression' named entity 'risk factors' named entity 'PCR' named entity 'episodes' named entity '100 days' named entity 'The majority' named entity 'risk' named entity 'ICU' named entity 'Testing' named entity 'ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION' named entity 'DIFFERENT' named entity 'TESTING' named entity 'RISK OF' named entity 'ERA' named entity 'EPISODES' named entity 'LOGISTIC REGRESSION' named entity 'ADMISSION' named entity 'PATIENTS' named entity 'TOTAL' named entity 'CHARACTERISTICS' named entity 'AUTOLOGOUS' named entity 'ICU' named entity 'SYMPTOMATIC' named entity 'PERIOD' named entity 'RESPIRATORY' named entity 'OUTCOMES' named entity 'WAS A' named entity 'PROGRESSING TO' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'MOLECULAR' named entity 'HOSPITAL' named entity 'CONFIDENCE INTERVAL' named entity 'ERA' named entity 'TESTING' named entity 'VIRAL' named entity 'DAYS' named entity 'RETROSPECTIVE' named entity 'INFECTIONS' named entity '4.1' named entity 'JANUARY' named entity 'RISK FACTORS' named entity '2015' named entity 'USING' named entity 'VIRAL RESPIRATORY TRACT INFECTION' named entity '2.1' named entity 'UPPER RESPIRATORY TRACT INFECTION' named entity 'MOLECULAR' named entity 'MORBIDITY AND MORTALITY' named entity 'EPIDEMIOLOGIC' named entity 'RATIO' named entity 'MULTIPLEX POLYMERASE CHAIN REACTION' named entity 'LOWER RESPIRATORY TRACT INFECTION' named entity 'IS A' named entity 'HSCT' named entity 'SIGNIFICANT' named entity 'ASSOCIATED WITH' named entity 'USED' named entity 'MAJORITY' named entity 'CAUSE' named entity 'STUDY' named entity 'DUE TO' named entity '382' named entity 'DIRECTLY' named entity 'DEATH' named entity 'MELBOURNE' named entity '100' named entity 'STATUS' named entity '28P' named entity 'REVIEW OF' named entity 'PRESENTED' named entity 'ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION' named entity 'INTENSIVE CARE UNIT' named entity 'IDENTIFIED' named entity 'INITIALLY' named entity 'INCREASED RISK'

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