About: Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells
Creator	Zhang, Gaiping Deng, Ruiguang Shi, Xibao Zhang, Xiaozhuan Jiang, Bo Wang, Aiping Chang, Yongzhe
Source	PMC
abstract	BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) induces one of most important devastating disease of swine worldwide, and the current methods poorly control it. Previous studies have indicated that the nonstructural protein 11 (nsp11) of PRRSV may be an important protein for the immune escape of PRRSV. RESULTS: Here, we firstly explored the effect of over-expression of nsp11 on PRRSV infection and found that over-expression of nsp11 enhanced the PRRSV titers while the small interfering RNA (siRNAs) specifically targeting nsp11 could reduce the PRRSV titers in MARC-145 cells. CONCLUSION: In conclusion, PRRSV nsp11 promotes PRRSV infection in MARC-145 cells and siRNAs targeting nsp11 may be a potential therapeutic strategy to control PRRSV in future.
has issue date	2016-06-06(xsd:dateTime)
bibo:doi	10.1186/s12917-016-0717-5
bibo:pmid	27268206
has license	cc-by
sha1sum (hex)	d3faa41624a8a99e5f600923cbe61fc457fb76a6
schema:url	https://doi.org/10.1186/s12917-016-0717-5
resource representing a document's title	Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells
has PubMed Central identifier	PMC4895886
has PubMed identifier	27268206
schema:publication	BMC Vet Res
resource representing a document's body	covid:d3faa41624a8a99e5f600923cbe61fc457fb76a6#body_text
is schema:about of	named entity 'future' named entity 'promotes' named entity 'swine' named entity 'INFECTION' named entity 'FUTURE' named entity 'ONE OF' named entity '145' named entity 'PREVIOUS' named entity 'FOUND' named entity 'IMPORTANT' named entity 'IMMUNE' named entity 'MAY BE A' named entity 'REDUCE' named entity 'SWINE' named entity 'PROTEIN ' named entity 'SIRNAS' named entity 'INDICATED' named entity 'MARC' named entity 'CONCLUSION' named entity 'EXPRESSION' named entity 'STUDIES' named entity 'FIRSTLY' named entity 'POTENTIAL' named entity 'WORLDWIDE' named entity 'RESULTS' named entity 'MAY BE' named entity 'HAVE' named entity 'PROTEIN ' named entity 'DISEASE' named entity 'CELLS' named entity 'PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS' named entity 'MARC' named entity 'POORLY' named entity 'PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS' named entity 'TO CONTROL' named entity 'SMALL INTERFERING RNA' named entity 'ESCAPE' named entity 'CELLS' named entity 'HERE' named entity 'ENHANCED' named entity 'CURRENT' named entity '145' named entity 'THERAPEUTIC' named entity 'EFFECT' named entity 'TARGETING' named entity 'METHODS' named entity 'BACKGROUND' named entity 'CONTROL' named entity 'STRATEGY' named entity 'INFECTION' named entity 'disease' named entity 'Conclusion' named entity 'targeting' named entity 'current' named entity 'infection' named entity 'immune' named entity 'siRNAs' named entity 'swine' named entity 'PRRSV' named entity 'siRNAs' named entity 'Porcine reproductive and respiratory syndrome virus' named entity 'PRRSV' named entity 'NaCl' named entity 'type I interferon' named entity 'IFN' named entity 'infection' named entity 'PVDF' named entity 'over-expression' named entity 'NLR' named entity 'transfection' named entity 'protease inhibitor' named entity 'therapeutic strategies' named entity 'mRNA' named entity 'GFP' named entity 'single-stranded RNA'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software