About: First report on fatal myocarditis associated with adenovirus infection in Cuba

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About: First report on fatal myocarditis associated with adenovirus infection in Cuba Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	First report on fatal myocarditis associated with adenovirus infection in Cuba
Creator	Casas, Inmaculada Acosta, Belsy Gonzalez, Grehete Gonzalez, Guelsys Goyenechea, Angel Guzmá, María Kourí, Vivian Lago, Mas Llop, Alina Martínez, Pedro Palerm, Lidice Pilar Perez Breñ, Ma Piñ, Alexander Rosario, Delfina Sarmiento, Luis Savó, Clara Valdé, Odalys
Source	Medline; PMC
abstract	Myocarditis is caused frequently by viral infections of the myocardium. In the past, enteroviruses (EV) were considered the most common cause of myocarditis in all age groups. Other viruses that cause myocarditis are adenovirus and influenza viruses. Parvovirus B19 infection is associated sometimes with myocarditis. Members of the Herpesviridae family, cytomegalovirus (CMV), and human herpesvirus 6 (HHV‐6) have been associated occasionally with myocarditis. During an atypical outbreak of acute febrile syndrome, eight children, with ages from 5 months to 15 years, died in cardiogenic shock due to myocarditis in July–August 2005, in the city of Havana, Cuba. Nested polymerase chain reaction (nPCR) and nested reverse transcription‐PCR (nRT‐PCR) were carried out on fresh heart muscle and lung tissue to analyze the genomic sequences of adenovirus, CMV, HHV‐6, herpes simplex virus, Epstein–Barr virus (EBV), varizella zoster virus, influenza virus A, B, C, respiratory syncytial virus (RSV) A and B, parainfluenza viruses, rhinoviruses, coronavirus, flaviruses and enteroviruses. Evidence was for the presence of the adenovirus genome in 6 (75%) of the children. Phylogenetic analyses of a conserved hexon gene fragment in four cases showed serotype 5 as the causal agent. No others viruses were detected. Histological examination was undertaken to detect myocardial inflammation. After exclusion of other possible causes of death, the results indicated that viral myocarditis was the cause of death in patients with adenovirus infection. J. Med. Virol. 80:1756–1761, 2008. © 2008 Wiley‐Liss, Inc.
has issue date	2008-08-19(xsd:dateTime)
bibo:doi	10.1002/jmv.21274
bibo:pmid	18712847
has license	no-cc
sha1sum (hex)	d4cf89744e7621a2039bf1eeb963d2f46661a198
schema:url	https://doi.org/10.1002/jmv.21274
resource representing a document's title	First report on fatal myocarditis associated with adenovirus infection in Cuba
has PubMed Central identifier	PMC7159136
has PubMed identifier	18712847
schema:publication	J Med Virol
resource representing a document's body	covid:d4cf89744e7621a2039bf1eeb963d2f46661a198#body_text
is schema:about of	named entity 'viral myocarditis' named entity 'Infection' named entity 'EXCLUSION OF' named entity 'rheumatic fever' named entity 'myocarditis' named entity 'inflammatory disease' named entity 'cardiac muscle' named entity 'sterile water' named entity 'heart disease' named entity 'Havana' named entity 'systemic diseases' named entity 'myocarditis' named entity 'infectious agents' named entity 'pediatric patients' named entity 'immunocompromised patients' named entity 'Paisley' named entity 'headache' named entity 'adenovirus' named entity 'inflammatory events' named entity 'viral disease' named entity 'ST segment' named entity 'underlying condition' named entity 'Cuba' named entity 'cardiogenic shock' named entity 'Adenovirus' named entity 'hexon' named entity 'heart tissue' named entity 'malaise' named entity 'clinical characteristics' named entity 'enterovirus infection' named entity 'tissue sections' named entity 'etiological' named entity 'cardiac transplantation' named entity 'Cuba' named entity 'influenza virus' named entity 'Parainfluenza' named entity 'distal' named entity 'infection' named entity 'serological tests' named entity 'hemagglutinating' named entity 'heart failure' named entity 'cardiomegaly' named entity 'Havana' named entity 'myocarditis' named entity 'PCR' named entity 'agarose gel electrophoresis' named entity 'echocardiogram' named entity 'lung' named entity 'genome' named entity 'viral RNA' named entity 'Acute myocarditis' named entity 'adenovirus' named entity 'organism' named entity 'Cuba' named entity 'Electrocardiographic' named entity 'cloned' named entity 'histological' named entity 'myocardium' named entity 'respiratory compromise' named entity 'virus' named entity 'myocarditis' named entity 'GenBank' named entity 'myocarditis' named entity 'la Habana' named entity 'PCR'

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