About: Impact of bacteremia prediction rule in CAP: Before and after study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Impact of bacteremia prediction rule in CAP: Before and after study
Creator	Kim, Byunghyun Kim, Joonghee Lee, Jieun Hwan, Yoo Hwang, Ji Lee, Jae
Source	Elsevier; Medline; PMC
abstract	Abstract Objective In cases of community acquired pneumonia (CAP), it has been known that blood cultures have low yields and rarely affect clinical outcomes. Despite many studies predicting the likelihood of bacteremia in CAP patients, those results have been rarely implemented in clinical practice, and use of blood culture in CAP is still increasing. This study evaluated impact of implementing a previously derived and validated bacteremia prediction rule. Methods In this registry-based before and after study, we used piecewise regression analysis to compare the blood culture rate before and after implementation of the prediction rule. We also compared 30-day mortality, emergency department (ED) length of stay, time-interval to initial antibiotics after ED arrival, and any changes to the antibiotics regimen as results of the blood cultures. In subgroup analysis, we compared two groups (with or without the use of the prediction rule) after implementation period, using propensity score matching. Results Following the implementation, the blood culture rate declined from 85.5% to 78.1% (P =0.003) without significant changes in 30-day mortality and antibiotics regimen. The interval to initial antibiotics (231min vs. 221min, P =0.362) and length of stay (1019min vs. 954min, P =0.354) were not significantly changed. In subgroup analysis, the group that use the prediction rule showed 25min faster antibiotics initiation (P =0.002) and 48min shorter length of stay (P =0.007) than the group that did not use the rule. Conclusion Implementation of the bacteremia prediction rule in CAP patients reduced the blood culture rate without affecting the 30-day mortality and antibiotics regimen.
has issue date	2018-05-31(xsd:dateTime)
bibo:doi	10.1016/j.ajem.2017.10.005
bibo:pmid	28988847
has license	els-covid
sha1sum (hex)	d5638f318aa00722f2cf711251d09bc297b98aa8
schema:url	https://doi.org/10.1016/j.ajem.2017.10.005
resource representing a document's title	Impact of bacteremia prediction rule in CAP: Before and after study
has PubMed Central identifier	PMC7127687
has PubMed identifier	28988847
schema:publication	The American Journal of Emergency Medicine
resource representing a document's body	covid:d5638f318aa00722f2cf711251d09bc297b98aa8#body_text
is schema:about of	named entity 'bacteremia' named entity 'study' named entity 'derived' named entity 'cases' named entity 'INITIAL' named entity 'BLOOD CULTURE' named entity 'RESULTS' named entity 'STUDY' named entity 'OBJECTIVE' named entity 'PATIENTS' named entity 'COMPARED' named entity 'FASTER' named entity 'BASED' named entity 'PREDICTING' named entity 'CHANGES' named entity 'EVALUATED' named entity 'SIGNIFICANT' named entity 'REGRESSION ANALYSIS' named entity 'FOLLOWING' named entity 'KNOWN' named entity 'INTERVAL' named entity 'PERIOD' named entity 'REGISTRY' named entity 'ANTIBIOTICS' named entity 'IMPLEMENTED' named entity 'CASES' named entity 'RARELY' named entity 'INITIATION' named entity 'METHODS' named entity 'INCREASING' named entity 'GROUP' named entity 'TO COMPARE' covid:arg/d5638f318aa00722f2cf711251d09bc297b98aa8 named entity 'BLOOD CULTURES' named entity 'MIN' named entity 'BACTEREMIA' named entity '0.003' named entity 'USE' named entity 'LIKELIHOOD' named entity 'PREDICTION' named entity 'STUDIES' named entity 'AFFECTING' named entity 'IMPLEMENTATION' named entity 'CLINICAL PRACTICE' named entity 'ARRIVAL' named entity 'PROPENSITY SCORE' named entity 'PREVIOUSLY' named entity 'CLINICAL OUTCOMES' named entity 'MATCHING' named entity 'USE OF' named entity 'SUBGROUP ANALYSIS' named entity 'RULE' named entity 'CAP' named entity 'ORIGINAL' named entity 'REGIMEN' named entity 'LOW' named entity 'TIME-INTERVAL' named entity 'VALIDATED' named entity 'CONCLUSION' named entity 'CHANGED' named entity 'USING' named entity 'DERIVED' named entity 'RATE' named entity '28P' named entity 'MORTALITY' named entity 'IMPACT' named entity 'GROUPS' named entity 'EMERGENCY DEPARTMENT' named entity 'CONTRIBUTION' named entity 'USED' named entity 'REDUCED' named entity 'COMMUNITY ACQUIRED PNEUMONIA' named entity 'HAVE' named entity 'DAY' named entity 'AFFECT' named entity 'LENGTH OF STAY'

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