About: Characterization of paneth cells in alpacas (Vicugna pacos, Mammalia, Camelidae)

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About: Characterization of paneth cells in alpacas (Vicugna pacos, Mammalia, Camelidae) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Characterization of paneth cells in alpacas (Vicugna pacos, Mammalia, Camelidae)
Creator	Barbeito, Claudio Falcón, Néstor Nishida, Fabián Ocampo, Jorge Rodríguez, José Zanuzzi, Carolina
Source	Elsevier; Medline; PMC
abstract	Abstract Paneth cells are secretory epithelial cells of the innate immune system of the intestine of several mammals, including alpacas. Little is known about the latter; thus, in the present study we described the morphology and histochemical characteristics of Paneth cells in healthy fetuses, and young and adult alpacas. For this purpose, samples of duodenum, jejunum and ileum were taken from 6 fetuses at different days of pregnancy (between days 221–330), 66 offsprings (between 0 and 45-days-old) and 5 adult alpacas (>2-years-old). Samples were fixed in 10% buffered formalin and processed for histological and morphometrical analysis using HE and Masson Trichomićs technique. Immunohistochemistry was used to identify Paneth cells using anti-lysozyme antibody. In addition, the lectinhistochemichal binding-pattern of Paneth celĺs granules was evaluated. Lyzozyme was immunohistochemically detected in the granules of Paneth cells from day 283 of pregnancy in all the small intestinal sections of the studied fetuses. In newborn alpacas Paneth cells were initially found in the duodenum, but the following days (days 18–21 after birth) they were also found in the ileum. Their size gradually increased after birth, but then no significant differences were found. In adult alpacas the number was lower than offsprings. We suggest that Paneth cells early differentiate in the small intestine of alpacas, and the increase in their number during the first two weeks of life strongly support their possible involvement in the intestinal defensive functions against the enteric diseases that occur during the lactancy stage.
has issue date	2016-08-31(xsd:dateTime)
bibo:doi	10.1016/j.tice.2016.04.003
bibo:pmid	27233914
has license	els-covid
sha1sum (hex)	d5b9af582e34ae2868f436ef8fcfc1318f7c2da2
schema:url	https://doi.org/10.1016/j.tice.2016.04.003
resource representing a document's title	Characterization of paneth cells in alpacas (Vicugna pacos, Mammalia, Camelidae)
has PubMed Central identifier	PMC7126146
has PubMed identifier	27233914
schema:publication	Tissue and Cell
resource representing a document's body	covid:d5b9af582e34ae2868f436ef8fcfc1318f7c2da2#body_text
is schema:about of	named entity 'Paneth cells' named entity 'samples' named entity 'Characterization' named entity 'Camelidae' named entity 'alpacas' named entity 'SMALL INTESTINAL' named entity 'ABOUT' named entity 'IMMUNOHISTOCHEMISTRY' named entity 'FOLLOWING' named entity 'FIXED' named entity 'INCREASED' named entity 'CHARACTERISTICS' named entity 'MORPHOLOGY' named entity 'SAMPLES' named entity 'SMALL INTESTINE' named entity 'NUMBER' named entity 'FUNCTIONS' named entity 'ENTERIC' named entity 'SUPPORT' named entity 'INNATE IMMUNE SYSTEM' named entity 'USED' named entity 'TO IDENTIFY' named entity 'PRESENT' named entity 'DAYS' named entity '283' named entity 'KNOWN' named entity 'ADS' named entity 'LOWER' named entity 'DETECTED' named entity 'BUT' named entity 'INITIALLY' named entity 'STAGE' named entity '330' named entity 'TWO WEEKS' named entity 'USING' named entity 'ANALYSIS' named entity 'FETUSES' named entity 'PANETH CELLS' named entity 'EPITHELIAL CELLS' named entity 'PANETH CELL' named entity 'INCREASE' named entity 'GRANULES' named entity '10%' named entity 'NEWBORN' named entity 'OCCUR' named entity 'SIGNIFICANT' named entity 'BUFFERED FORMALIN' named entity 'OFFSPRINGS' named entity 'EARLY' named entity 'BIRTH' named entity 'TAKEN' named entity 'PANETH CELLS' named entity 'CAMELIDAE' named entity 'DAY' named entity 'TECHNIQUE' named entity 'INTESTINE' named entity 'DIFFERENTIATE' named entity 'HEALTHY' named entity 'PROCESSED' named entity 'JEJUNUM' named entity '3E2' named entity 'DISEASES' covid:arg/d5b9af582e34ae2868f436ef8fcfc1318f7c2da2 named entity 'LYSOZYME ANTIBODY' named entity 'STUDY' named entity 'MASSON' named entity 'INVOLVEMENT' named entity 'MAMMALIA' named entity 'ALPACAS' named entity 'CHARACTERIZATION' named entity 'ALPACAS' named entity 'MAMMALS' named entity 'LITTLE' named entity 'INTESTINAL' named entity 'YEARS' named entity 'EVALUATED'

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