About: Low mortality rates related to respiratory virus infections after bone marrow transplantation

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Low mortality rates related to respiratory virus infections after bone marrow transplantation
Creator	Pannuti, C Da Rocha, I Dulley, F Machado, C Mendes, Ava Santos, Mfm Sturaro, D Vilas Boas, L
source	Medline; PMC
abstract	Respiratory viruses (RVs) frequently cause severe respiratory disease in bone marrrow transplant (BMT) recipients. To evaluate the frequency of RV, nasal washes were collected year-round from BMT recipients with symptoms of upper respiratory tract infection (URI). Direct immunofluorescence assay was performed for respiratory syncytial virus (RSV), influenza (Flu) A and B, adenovirus and parainfluenza (Paraflu) virus. Patients with RSV pneumonia or with upper RSV infection, but considered at high risk for developing RSV pneumonia received aerosolized ribavirin. Oseltamivir was given to patients with influenza. A total of 179 patients had 392 episodes of URI. In all, 68 (38%) tested positive: RSV was detected in 18 patients (26.4%), Flu B in 17 (25%), Flu A in 11 (16.2%) and Paraflu in 7 (10.3%). A total of 14 patients (20.6%) had multiple RV infections or coinfection. RSV pneumonia developed in 55.5% of the patients with RSV-URI. One of the 15 patients (6.6%) with RSV pneumonia died. Influenza pneumonia was diagnosed in three patients (7.3%). RSV and influenza infections peaked in fall–winter and winter–spring months, respectively. We observed decreased rates of influenza and parainfluenza pneumonia and low mortality because of RSV pneumonia. The role of antiviral interventions such as aerosolized ribavirin and new neuraminidase inhibitors remains to be defined in randomized trials.
has issue date	2003-04-11(xsd:dateTime)
bibo:doi	10.1038/sj.bmt.1703900
bibo:pmid	12692610
has license	no-cc
sha1sum (hex)	d648ec74fb7e23007d1c848fbb9580cc671916d1
schema:url	https://doi.org/10.1038/sj.bmt.1703900
resource representing a document's title	Low mortality rates related to respiratory virus infections after bone marrow transplantation
has PubMed Central identifier	PMC7091922
has PubMed identifier	12692610
schema:publication	Bone Marrow Transplant
resource representing a document's body	covid:d648ec74fb7e23007d1c848fbb9580cc671916d1#body_text
is schema:about of	named entity 'pneumonia' named entity 'RSV' named entity 'upper' named entity 'randomized trials' named entity 'mortality rates' named entity 'Infections' named entity 'FREQUENCY' named entity 'TESTED' named entity 'ROUND' named entity 'EPISODES' named entity 'NEW' named entity 'ONE OF' named entity 'INFECTIONS' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'BUT' named entity 'MONTHS' named entity 'UPPER' named entity 'PARAINFLUENZA' named entity 'BONE' named entity 'OBSERVED' named entity 'INTERVENTIONS' named entity 'DEVELOPING' named entity 'DIRECT IMMUNOFLUORESCENCE' named entity 'RANDOMIZED TRIALS' named entity 'FALL' named entity 'HIGH RISK' named entity 'SPRING' named entity 'TRANSPLANT' named entity 'DETECTED' named entity 'RECEIVED' named entity 'BMT' named entity 'ANTIVIRAL' named entity 'LOW' named entity 'BONE MARROW TRANSPLANTATION' named entity 'RESPIRATORY VIRUS' named entity '179' named entity 'FLU' named entity 'RSV' named entity 'POSITIVE' named entity '287' named entity 'PATIENTS' named entity 'PNEUMONIA' named entity 'RSV PNEUMONIA' named entity 'COINFECTION' named entity 'NEURAMINIDASE INHIBITORS' named entity 'RELATED' named entity 'DIAGNOSED' named entity 'ADENOVIRUS' named entity 'TOTAL' named entity 'DEFINED' named entity 'LOW' named entity 'INFECTIONS' named entity 'MORTALITY RATES' named entity 'URI' named entity 'NASAL' named entity 'ROLE' named entity 'SEVERE' named entity 'FREQUENTLY' named entity 'INFLUENZA PNEUMONIA' named entity 'EVALUATE' named entity 'GIVEN' named entity 'PEAKED' named entity 'RESPIRATORY DISEASE' named entity 'COLLECTED' named entity '392' named entity 'RESPIRATORY VIRUSES' named entity 'YEAR' named entity 'RSV INFECTION' named entity 'DIED' named entity 'PARAFLU' named entity 'INFLUENZA' named entity 'RIBAVIRIN' named entity 'WINTER' named entity 'CAUSE'

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