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  • Phylogenetic analysis of SARS coronavirus isolates based on the spike gene and protein sequence using Neighbor-Joining, maximum likelihood and Bayesian inference methods indicated that a recent human SARS-CoV isolate was closer to some human SARS-CoV isolates from earlier epidemic phase than to the SARS-CoV-like viruses isolated from wild animals during previous epidemic phase. A reasonable judgment based on phylogenetic relationship and sequence variations it is likely that the recent human SARS-CoV isolate is closer to an unknown SARS-CoV predecessor.
Subject
  • Virology
  • Phylogenetics
  • Cluster analysis algorithms
  • Logic and statistics
  • Sarbecovirus
  • Chiroptera-borne diseases
  • Infraspecific virus taxa
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