About: Treating nasal symptoms associated with rhinitis using the intranasal herbal ointment Biyeom‐go: A prospective observational study

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About: Treating nasal symptoms associated with rhinitis using the intranasal herbal ointment Biyeom‐go: A prospective observational study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Treating nasal symptoms associated with rhinitis using the intranasal herbal ointment Biyeom‐go: A prospective observational study
Creator	Jung, Jeeyoun Kim, Sungha Kwon, Ojin Kim, Young-Eun Jung, Young Lee, Min Kang, Jeong-In Kim, Hye-Lin Lee, Dong-Hyo Lee, Jung-Eun So, \| Son, Mi Yeum, Chang-Sub
Source	Medline; PMC
abstract	OBJECTIVES: The aim of the current study was to investigate the effectiveness and clinical feasibility of Biyeom‐go for the treatment of nasal symptoms associated with rhinitis. DESIGN: Prospective observational study. SETTING: This study was conducted at the Woosuk Korean Medicine Medical Center in South Korea. PARTICIPANTS: Fifty‐eight patients with rhinitis participated in this study. All patients received Biyeom‐go treatment >3 times daily for a total of 4 weeks. MAIN OUTCOME MEASURES: The primary outcome was the total nasal symptom score. Mini‐rhinoconjunctivitis quality of life questionnaire, nasal endoscopy index, total serum immunoglobulin E levels and immunologic factors in nasal lavage fluid were also measured. RESULTS: Biyeom‐go administration was associated with significant improvements in total nasal symptoms scores (P < .0001) and mini‐rhinoconjunctivitis quality of life questionnaire scores (P < .0001) in a time‐dependent manner. The nasal endoscopy index also significantly improved at weeks 2 (P = .0049), 3 (P < .0001) and 4 (P = .0001) after Biyeom‐go treatment. Significantly, increased interleukin‐2 levels (P = .005) and decreased interleukin‐8, chemokine (C‐C motif) ligand (CCL) 5, chemokine (C‐X‐C motif) ligand (CXCL) 9, CCL2 and CXCL10 levels were observed in the nasal lavage fluid. CONCLUSIONS: The present findings suggest that Biyeom‐go may be beneficial for the management of rhinitis symptoms and rhinitis‐associated quality of life. Further well‐designed randomised controlled trials are needed to evaluate the effectiveness of Biyeom‐go for rhinitis.
has issue date	2019-10-29(xsd:dateTime)
bibo:doi	10.1111/coa.13425
bibo:pmid	31468673
has license	cc-by-nc-nd
sha1sum (hex)	d89b71dc9725043b0a554e5b55791ef59e51d05a
schema:url	https://doi.org/10.1111/coa.13425
resource representing a document's title	Treating nasal symptoms associated with rhinitis using the intranasal herbal ointment Biyeom‐go: A prospective observational study
has PubMed Central identifier	PMC6916331
has PubMed identifier	31468673
schema:publication	Clin Otolaryngol
resource representing a document's body	covid:d89b71dc9725043b0a554e5b55791ef59e51d05a#body_text
is schema:about of	named entity 'STUDY' named entity 'EFFECTIVENESS' named entity 'ointment' named entity 'INTRANASAL' named entity 'NASAL SYMPTOMS' named entity 'OINTMENT' named entity 'USING' named entity 'ASSOCIATED WITH' named entity 'PROSPECTIVE OBSERVATIONAL STUDY' named entity 'RHINITIS' named entity 'AIM' named entity 'TO INVESTIGATE' named entity 'HERBAL' named entity 'TREATING' named entity 'CURRENT' named entity 'RHINITIS' covid:arg/d89b71dc9725043b0a554e5b55791ef59e51d05a named entity 'investigate' named entity 'herbal' named entity 'rhinitis' named entity 'otitis media' named entity 'rhinorrhea' named entity 'IgE' named entity 'interleukin' named entity 'CXCL9' named entity 'rhinitis' named entity 'nasal cavity' named entity 'nasal congestion' named entity 'clinical practice' named entity 'Glycyrrhizae Radix' named entity 'ointment' named entity 'CCL5' named entity 'P<.05' named entity 'inflammatory' named entity 'rhinitis' named entity 'rhinitis' named entity 'inflammation' named entity 'learning impairment' named entity 'adverse effects' named entity 'rhinosinusitis' named entity 'East Asian' named entity 'sneezing' named entity 'TNF' named entity 'intranasal' named entity 'rhinitis' named entity 'histamines' named entity 'CCL2' named entity 'cytokines' named entity 'AEs' named entity 'rhinitis' named entity 'common cold' named entity 'missing data' named entity 'eosinophil' named entity 'adverse events' named entity 'IL-' named entity 'nasal inflammation' named entity 'asthma' named entity 'CXCL10' named entity 'Intranasal' named entity 'rhinitis' named entity 'intranasal' named entity 'ointment' named entity 'observational study' named entity 'aim' named entity 'effectiveness' named entity 'rhinitis' named entity 'nasal' named entity 'observational study' named entity 'rhinitis'

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