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About:
Efficient Separation of Four Antibacterial Diterpenes from the Roots of Salvia Prattii Using Non-Aqueous Hydrophilic Solid-Phase Extraction Followed by Preparative High-Performance Liquid Chromatography
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An Entity of Type :
schema:ScholarlyArticle
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wasabi.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Efficient Separation of Four Antibacterial Diterpenes from the Roots of Salvia Prattii Using Non-Aqueous Hydrophilic Solid-Phase Extraction Followed by Preparative High-Performance Liquid Chromatography
Creator
Cui, Yulei
Dang, Jun
Jiao, Lijin
Liu, Zenggen
Mei, Lijuan
Pei, Jinjin
Shao, Yun
Tao, Yanduo
Wang, Qilan
Wang, Weidong
Yue, Huilan
Id, †
source
PMC
abstract
An efficient preparative procedure for the separation of four antibacterial diterpenes from a Salvia prattii crude diterpenes-rich sample was developed. Firstly, the XION hydrophilic stationary phase was chosen to separate the antibacterial crude diterpenes-rich sample (18.0 g) into three fractions with a recovery of 46.1%. Then, the antibacterial fractions I (200 mg), II (200 mg), and III (150 g) were separated by the Megress C18 preparative column, and compounds tanshinone IIA (80.0 mg), salvinolone (62.0 mg), cryptotanshinone (70.0 mg), and ferruginol (68.0 mg) were produced with purities greater than 98%. The procedure achieved large-scale preparation of the four diterpenes with high purity, and it could act as a reference for the efficient preparation of active diterpenes from other plant extracts.
has issue date
2018-03-09
(
xsd:dateTime
)
bibo:doi
10.3390/molecules23030623
bibo:pmid
29522496
has license
cc-by
sha1sum (hex)
d9a66cbdd96e0bce18bc370c96ef5e71c5a7a27d
schema:url
https://doi.org/10.3390/molecules23030623
resource representing a document's title
Efficient Separation of Four Antibacterial Diterpenes from the Roots of Salvia Prattii Using Non-Aqueous Hydrophilic Solid-Phase Extraction Followed by Preparative High-Performance Liquid Chromatography
has PubMed Central identifier
PMC6017395
has PubMed identifier
29522496
schema:publication
Molecules
resource representing a document's body
covid:d9a66cbdd96e0bce18bc370c96ef5e71c5a7a27d#body_text
is
schema:about
of
named entity 'III'
named entity 'produced'
named entity 'reference'
named entity 'Hydrophilic'
named entity 'Efficient'
named entity 'Diterpenes'
named entity 'Roots'
named entity 'ANTIBACTERIAL'
covid:arg/d9a66cbdd96e0bce18bc370c96ef5e71c5a7a27d
named entity 'ACTIVE'
named entity 'EFFICIENT'
named entity 'HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY'
named entity 'SEPARATION'
named entity 'GREATER THAN'
named entity 'FIRSTLY'
named entity 'DITERPENES'
named entity 'PLANT EXTRACTS'
named entity 'C18'
named entity 'EFFICIENT'
named entity 'FOLLOWED BY'
named entity 'AQUEOUS'
named entity 'RICH'
named entity 'STATIONARY PHASE'
named entity '2818'
named entity 'ANTIBACTERIAL'
named entity 'SEPARATION'
named entity 'MOLECULES'
named entity 'HYDROPHILIC'
named entity 'ROOTS'
named entity 'NON-'
named entity 'SALVIA PRATTII'
named entity 'III'
named entity 'SALVINOLONE'
named entity 'HYDROPHILIC'
named entity 'FRACTIONS'
named entity 'TO SEPARATE'
named entity 'CHOSEN'
named entity 'PURITY'
named entity 'HIGH'
named entity 'PROCEDURE'
named entity 'ACT'
named entity 'SEPARATED'
named entity 'RECOVERY'
named entity '2880'
named entity '28150'
named entity 'SALVIA PRATTII'
named entity 'SAMPLE'
named entity 'CRYPTOTANSHINONE'
named entity 'MG%'
named entity 'SOLID-PHASE EXTRACTION'
named entity 'PREPARATION'
named entity 'FERRUGINOL'
named entity 'REFERENCE'
named entity 'COLUMN'
named entity 'SCALE'
named entity 'TANSHINONE IIA'
named entity 'DITERPENES'
named entity 'USING'
named entity 'LARGE'
named entity 'plant'
named entity 'extracts'
named entity 'diterpenes'
named entity 'XION'
named entity 'ferruginol'
named entity 'diterpenes'
named entity '70.0'
named entity 'Antibacterial'
named entity '250 mm'
named entity 'diterpenes'
named entity 'rotary evaporator'
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