About: Expedited SARS‐CoV‐2 Screening of Donors and Recipients Supports Continued Solid Organ Transplant

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About: Expedited SARS‐CoV‐2 Screening of Donors and Recipients Supports Continued Solid Organ Transplant Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Expedited SARS‐CoV‐2 Screening of Donors and Recipients Supports Continued Solid Organ Transplant
Creator	Cent, Anne Jerome, Keith Author, Corresponding Limaye, Ajit Lieberman, J Greninger, Alex Lieberman, Joshua Mays, James Bankson, Daniel Bell, Deborah Orcids, Wells, Candy
Source	Medline; PMC; WHO
abstract	Universal screening of potential organ donors and recipients for SARS‐CoV‐2 is now recommended prior to transplantation in the United States during the COVID‐19 pandemic. Challenges have included limited testing capacity, short windows of organ viability, brief lead time for notification of potential organ recipients, and the need to test lower respiratory donor specimens to optimize sensitivity. In an early US epicenter of the outbreak, we designed and implemented a system to expedite this testing and here report results from the first three weeks. The process included a Laboratory Medicine designee for communication with organ recovery and transplant clinical staff, specialized sample labeling and handoff, and priority processing. Thirty‐two organs recovered from 14 of 17 screened donors were transplanted versus 70 recovered from 23 donors during the same period in 2019. No pre‐transplant or organ donors tested positive for SARS‐CoV‐2. Median turnaround time from specimen receipt was 6.8h (donors), 6.5h (recipients): 4.5h faster than daily inpatient median. No organ recoveries or transplants were disrupted by a lack of SARS‐CoV‐2 testing. Waitlist inactivations for COVID‐19 precautions were reduced in our region. Systems that include specialized ordering pathways and adequate testing capacity can support continued organ transplantation even in a SARS‐CoV‐2 hyperendemic area.
has issue date	2020-06-01(xsd:dateTime)
bibo:doi	10.1111/ajt.16081
bibo:pmid	32476285
has license	no-cc
sha1sum (hex)	d9ab728829686b4140d89a2df364243ae2942d85
schema:url	https://doi.org/10.1111/ajt.16081
resource representing a document's title	Expedited SARS‐CoV‐2 Screening of Donors and Recipients Supports Continued Solid Organ Transplant
has PubMed Central identifier	PMC7300788
has PubMed identifier	32476285
schema:publication	Am J Transplant
resource representing a document's body	covid:d9ab728829686b4140d89a2df364243ae2942d85#body_text
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