About: Prolonged depletion of circulating CD4+ T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogs

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Prolonged depletion of circulating CD4+ T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Prolonged depletion of circulating CD4+ T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogs
Creator	Buonavoglia, Canio Decaro, Nicola Elia, Gabriella Mari, Viviana Losurdo, Michele Marinaro, Mariarosaria Rezza, Giovanni Tarsitano, Elvira Bellacicco, Anna
source	Elsevier; Medline; PMC
abstract	Abstract A hypervirulent strain (CB/05) of canine coronavirus was employed to infect oronasally 11-week-old pups. Peripheral blood monocytes (CD14+), T lymphocytes (CD4+ and CD8+) and B lymphocytes (CD21+) were studied by flow cytometry within 5 days post-infection (p.i.) and at later time points. Infection with CB/05 resulted in a profound depletion of T cells and a slight loss of B cells in the first week p.i. In particular, while the CD8+ and the B lymphocytes returned to baseline levels by day 7 p.i., the CD4+ T cells remained significantly low until day 30 p.i. and recovered completely only at day 60 p.i. Monocytosis was also observed after CB/05 infection with a peak at day 5 p.i. The prolonged depletion of peripheral CD4+ T cells did not alter the levels of serum IgG or IgM. The impact of CB/05 infection on the immune performance of infected pups is discussed.
has issue date	2010-09-30(xsd:dateTime)
bibo:doi	10.1016/j.virusres.2010.06.006
bibo:pmid	20558216
has license	els-covid
sha1sum (hex)	da85a49fa9679f0f3cf4d1e16f96524a5515ef9b
schema:url	https://doi.org/10.1016/j.virusres.2010.06.006
resource representing a document's title	Prolonged depletion of circulating CD4+ T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogs
has PubMed Central identifier	PMC7114409
has PubMed identifier	20558216
schema:publication	Virus Research
resource representing a document's body	covid:da85a49fa9679f0f3cf4d1e16f96524a5515ef9b#body_text
is schema:about of	named entity 'CANINE CORONAVIRUS' named entity 'CD14' named entity 'dogs' named entity 'PERIPHERAL BLOOD' named entity 'TO INFECT' named entity 'INFECTION' named entity '28P' named entity 'CIRCULATING' named entity 'OLD' named entity 'POINTS' named entity 'POST' named entity 'DOGS' named entity 'MONOCYTOSIS' named entity 'CORONAVIRUS INFECTION' named entity 'CD4' named entity 'CANINE CORONAVIRUS' named entity 'TIME' named entity 'STRAIN' named entity 'T LYMPHOCYTES' named entity 'PROLONGED' named entity 'DEPLETION' named entity 'ACUTE' named entity 'BLOOD MONOCYTES' named entity 'EMPLOYED' named entity 'T LYMPHOCYTES' named entity 'CD8' named entity 'WEEK' named entity 'LATER' named entity 'B LYMPHOCYTES' named entity 'PUPS' named entity 'DAYS' named entity 'FLOW CYTOMETRY' named entity 'Infection' named entity 'pups' named entity 'infection' named entity 'lymphocytes' named entity 'employed' named entity 'innate immune' named entity 'blood cells' named entity 'CD8 +' named entity 'CD8 +' named entity 'viral infections' named entity 'fever' named entity 'monocyte' named entity 'lymphocyte subsets' named entity 'dog' named entity 'HIV infection' named entity 'FITC' named entity 'apoptosis' named entity 'infectious diseases' named entity 'lamina propria' named entity 'flow cytometry' named entity 'TNF-alpha' named entity 'infectious agents' named entity 'receptor' named entity 'neutrophils' named entity 'atrophy' named entity 'hypervirulent' named entity 'infection' named entity 'CD4 +' named entity 'IgG' named entity 'thymus' named entity 'Ahr' named entity 'Gourgeon' named entity 'confidence level' named entity 'FIPV' named entity 'lymphocytes' named entity 'immune responses' named entity 'serum' named entity 'CD8' named entity 'CD4 +' named entity 'mesenteric lymph nodes' named entity 'CD14'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software