About: The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel

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About: The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel
Creator	Gaydos, Charlotte Eagan, Aaron Gibert, Cynthia Nyquist, Ann-Christine Rodrigues-Barradas, Maria Savor-Price, Connie Radonovich, Lewis Cummings, Derek Shaffer, Ronald Bessesen, Mary Gorse, Geoffrey Perl, Trish Reich, Nicholas Simberkoff, Michael
Source	Medline; PMC
abstract	BACKGROUND: Although N95 filtering facepiece respirators and medical masks are commonly used for protection against respiratory infections in healthcare settings, more clinical evidence is needed to understand the optimal settings and exposure circumstances for healthcare personnel to use these devices. A lack of clinically germane research has led to equivocal, and occasionally conflicting, healthcare respiratory protection recommendations from public health organizations, professional societies, and experts. METHODS: The Respiratory Protection Effectiveness Clinical Trial (ResPECT) is a prospective comparison of respiratory protective equipment to be conducted at multiple U.S. study sites. Healthcare personnel who work in outpatient settings will be cluster-randomized to wear N95 respirators or medical masks for protection against infections during respiratory virus season. Outcome measures will include laboratory-confirmed viral respiratory infections, acute respiratory illness, and influenza-like illness. Participant exposures to patients, coworkers, and others with symptoms and signs of respiratory infection, both within and beyond the workplace, will be recorded in daily diaries. Adherence to study protocols will be monitored by the study team. DISCUSSION: ResPECT is designed to better understand the extent to which N95s and MMs reduce clinical illness among healthcare personnel. A fully successful study would produce clinically relevant results that help clinician-leaders make reasoned decisions about protection of healthcare personnel against occupationally acquired respiratory infections and prevention of spread within healthcare systems. TRIAL REGISTRATION: The trial is registered at clinicaltrials.gov, number NCT01249625 (11/29/2010).
has issue date	2016-06-02(xsd:dateTime)
bibo:doi	10.1186/s12879-016-1494-2
bibo:pmid	27255755
has license	cc-by
sha1sum (hex)	dbf76534e0b330bb0f155296e251c1e7031c90c0
schema:url	https://doi.org/10.1186/s12879-016-1494-2
resource representing a document's title	The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel
has PubMed Central identifier	PMC4890247
has PubMed identifier	27255755
schema:publication	BMC Infect Dis
resource representing a document's body	covid:dbf76534e0b330bb0f155296e251c1e7031c90c0#body_text
is schema:about of	named entity 'PROTOCOLS' named entity 'SITES' named entity 'MASKS' named entity 'BACKGROUND' named entity 'COWORKERS' named entity 'MEDICAL' named entity 'OUTPATIENT' named entity 'LED' named entity 'MONITORED' named entity 'INFECTIONS' named entity 'CONFIRMED' named entity 'PERSONNEL' named entity 'PROFESSIONAL' named entity 'PROTECTIVE EQUIPMENT' named entity 'RESPIRATORY PROTECTION' named entity 'LABORATORY' named entity 'PATIENTS' named entity 'PROTECTION' named entity 'ADHERENCE' named entity 'RESPIRATORY VIRUS' named entity 'commonly' named entity 'experts' named entity 'influenza-like illness' named entity 'study' named entity 'sites' named entity 'prospective' named entity 'randomized' covid:arg/dbf76534e0b330bb0f155296e251c1e7031c90c0 named entity 'RESPIRATORY INFECTIONS' named entity 'COMPARISON' named entity 'NEEDED' named entity 'USE' named entity 'STUDY' named entity 'THESE' named entity 'RESPIRATORY' named entity 'LACK' named entity 'SOCIETIES' named entity 'RESPIRATORY INFECTION' named entity 'PARTICIPANT' named entity 'ACUTE RESPIRATORY ILLNESS' named entity 'RESEARCH' named entity 'EVIDENCE' named entity 'RECOMMENDATIONS' named entity 'PROSPECTIVE' named entity 'EXPOSURES' named entity 'HEALTHCARE' named entity 'COMPARISON' named entity 'EFFECTIVENESS' named entity 'RESPIRATORY PROTECTION' named entity 'PERSONNEL' named entity 'CLINICAL TRIAL' named entity 'RESPIRATOR' named entity 'RESPIRATORY INFECTIONS' named entity 'RESPIRATORS' named entity 'CLINICAL TRIAL' named entity 'CLINICAL' named entity 'SYMPTOMS AND SIGNS' named entity 'N95' named entity 'DEVICES' named entity 'OUTCOME MEASURES' named entity 'RANDOMIZED' named entity 'OCCASIONALLY' named entity 'INFLUENZA-LIKE ILLNESS' named entity 'HEALTH ORGANIZATIONS' named entity 'GERMANE' named entity 'SETTINGS' named entity 'TEAM' named entity 'RECORDED'

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