About: Persistence of SARS-CoV-2 in the first trimester placenta leading to vertical transmission and fetal demise from an asymptomatic mother

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About: Persistence of SARS-CoV-2 in the first trimester placenta leading to vertical transmission and fetal demise from an asymptomatic mother Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Persistence of SARS-CoV-2 in the first trimester placenta leading to vertical transmission and fetal demise from an asymptomatic mother
Creator	Patel, Vainav Mahale, Smita Bhagat, Sharad Bhide, Anshul Bhor, Vikrant Gaikwad, ; Gaikwad, Pradip Gajbhiye, Rahul Manisha Gandhewar, ; Modi, Deepak Shende, Prajakta Ukey, Pawankumar
source	MedRxiv
abstract	Coronaviruses infect the respiratory tract and are known to survive in these tissues during the clinical course of infection. However, how long can SARS-CoV-2 survive in the tissues is hitherto unknown. Herein, we report a case where the virus is detected in the first trimester placental cytotrophoblast and syncytiotrophoblasts five weeks after the asymptomatic mother cleared the virus from the respiratory tract. This first trimester placental infection was vertically transmitted as the virus was detected in the amniotic fluid and fetal membranes. This congenitally acquired SARS-CoV-2 infection was associated with hydrops and fetal demise. This is the first study providing concrete evidences towards persistent tissue infection of SARS-CoV-2, its congenital transmission in early pregnancy leading to intrauterine fetal death.
has issue date	2020-08-21(xsd:dateTime)
bibo:doi	10.1101/2020.08.18.20177121
has license	medrxiv
sha1sum (hex)	dd2070c1536b1147b3bb87ba90f22d1d20fc871c
schema:url	https://doi.org/10.1101/2020.08.18.20177121
resource representing a document's title	Persistence of SARS-CoV-2 in the first trimester placenta leading to vertical transmission and fetal demise from an asymptomatic mother
resource representing a document's body	covid:dd2070c1536b1147b3bb87ba90f22d1d20fc871c#body_text
is schema:about of	named entity 'concrete' named entity 'tissues' named entity 'infection' named entity 'This' named entity 'SARS-CoV-2' named entity 'vertically transmitted' named entity 'mother' named entity 'leading' named entity 'TISSUES' named entity 'EARLY PREGNANCY' named entity 'PLACENTAL CYTOTROPHOBLAST' named entity 'MOTHER' named entity 'SARS-CoV-2' named entity 'cleared' named entity 'asymptomatic' named entity 'infection' named entity 'persistent' named entity 'intrauterine fetal death' named entity 'virus' named entity 'SARS-CoV-2' named entity 'cytotrophoblast' named entity 'Coronaviruses' named entity 'congenital' named entity 'syncytiotrophoblasts' named entity 'infection' named entity 'virus' named entity 'respiratory tract' named entity 'asymptomatic' named entity 'fetal demise' named entity 'fetus' named entity 'leucocytes' named entity 'blood vessels' named entity 'medRxiv' named entity 'mother to child transmission' named entity 'Fluorescence in situ hybridization' named entity 'infection' named entity 'infection' named entity 'placental' named entity 'Rubella' named entity 'cell types' named entity 'COVID' named entity 'amniotic fluid' named entity 'initial infection' named entity 'SARS-CoV-2' named entity 'CD147' named entity 'tested positive' named entity 'placental' named entity 'placental' named entity 'villi' named entity 'transport medium' named entity 'histopathology' named entity 'viral infections' named entity 'fetal demise' named entity 'placental' named entity 'monoclonal antibodies' named entity 'medRxiv' named entity 'fetal demise' named entity 'nasopharyngeal swab' named entity 'anticardiolipin antibodies' named entity 'peer review' named entity 'IgG antibodies' named entity 'gene' named entity 'hydrops fetalis' named entity 'Rh positive' named entity 'Inflammatory' named entity 'fetal membrane' named entity 'vertically transmitted' named entity 'vertical transmission' named entity 'SARS-CoV-2' named entity 'viremia' named entity 'SARS-CoV-2' named entity 'ultrasound' named entity 'fetal demise' named entity 'IgG'

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