About: The spontaneous breathing trial is of low predictive value regarding spontaneous breathing ability in subjects with prolonged, unsuccessful weaning

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About: The spontaneous breathing trial is of low predictive value regarding spontaneous breathing ability in subjects with prolonged, unsuccessful weaning Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The spontaneous breathing trial is of low predictive value regarding spontaneous breathing ability in subjects with prolonged, unsuccessful weaning
Creator	Buerke, Redaktion Storre, J Callegari, · Heilf, · Huttmann, · Magnet, Siegen Schwarz, · Windisch, ·
Source	PMC
abstract	BACKGROUND: The spontaneous breathing trial (SBT) is a well-established diagnostic test for predicting extubation failure in intubated intensive care unit (ICU) patients. However, the SBT has not been evaluated in a specific cohort of tracheostomized patients in whom weaning is prolonged and ultimately unsuccessful. OBJECTIVE: The aim of the trial was to investigate the relevance of SBT failure criteria in chronic respiratory failure subjects undergoing long-term invasive home mechanical ventilation following tracheostomy and weaning failure. METHODS: Measurement of all established failure criteria including pneumotachygraphical assessment of the rapid shallow breathing index (RSBI) took place during an SBT. The decision to continue spontaneous breathing was based on failure criteria as well as the subjective willingness of the patient. RESULTS: Fifteen subjects with a median age of 58 years (interquartile range [IQR] 44–74) were studied; 10 with COPD, 4 with neuromuscular diseases and 1 with both. Twelve subjects met the SBT failure criteria within 30 min, but one third of these subjects were still able to continue with spontaneous breathing. In contrast, 3 subjects could not be weaned despite the SBT being successful. An increased RSBI was the most frequently observed SBT failure criterion (57% of all SBT). However, the SBT varied substantially in individual subjects who were able to sustain spontaneous breathing, despite having reached the cut-off for SBT failure. CONCLUSION: The SBT was of low predictive value regarding spontaneous breathing ability in chronic respiratory failure subjects with prolonged, unsuccessful weaning.
has issue date	2019-08-07(xsd:dateTime)
bibo:doi	10.1007/s00063-019-0599-y
bibo:pmid	31392353
has license	no-cc
sha1sum (hex)	de8b660647faf57b814d543b5c942ee34d5294db
schema:url	https://doi.org/10.1007/s00063-019-0599-y
resource representing a document's title	The spontaneous breathing trial is of low predictive value regarding spontaneous breathing ability in subjects with prolonged, unsuccessful weaning
has PubMed Central identifier	PMC7223831
has PubMed identifier	31392353
schema:publication	Med Klin Intensivmed Notfmed
resource representing a document's body	covid:de8b660647faf57b814d543b5c942ee34d5294db#body_text
is schema:about of	named entity 'subjects' named entity 'Klinik' named entity 'weaning' named entity 'SBT' named entity 'SBT' named entity 'breathing frequency' named entity 'ICU' named entity 'SBT' named entity 'mechanical ventilation' named entity 'weaning' named entity 'weaning' named entity 'SBT' named entity 'neuromuscular diseases' named entity 'HMV' named entity 'rapid shallow breathing index' named entity 'non-normally distributed' named entity 'weaning' named entity 'shallow breathing' named entity 'Cologne' named entity 'weaning' named entity 'RSBI' named entity 'Germany' named entity 'SBT' named entity 'Clinical Trials Register' named entity 'SBT' named entity '2.0' named entity 'SBT' named entity 'weaning' named entity 'SpO2' named entity 'cyanosis' named entity 'RSBI' named entity 'Germany' named entity 'SBT' named entity 'SBT' named entity 'SBT' named entity 'Statistical significance' named entity 'intubated' named entity 'rapid shallow breathing index' named entity 'ventilator' named entity 'Switzerland' named entity 'outpatient setting' named entity 'RSBI' named entity 'Therwil' named entity 'neuromuscular disorders' named entity 'SBT' named entity 'heat and moisture exchanger' named entity 'SBT' named entity 'SBT' named entity 'tidal volume' named entity 'weaning' named entity 'SBT' named entity 'weaning' named entity 'SBT' named entity 'Blood pressure' named entity 'ICU' named entity 'intubated' named entity 'clinical practice' named entity 'weaning' named entity 'oxygen saturation' named entity 'Weaning' named entity 'tracheostomy' named entity 'weaning' named entity 'ICU' named entity 'weaning' named entity 'Statistical significance' named entity 'RSBI' named entity 'rapid shallow breathing index' named entity 'dyspnoea' named entity 'multiple testing' named entity 'mechanical ventilation' named entity 'invasive mechanical ventilation' named entity 'dyspnoea' named entity 'spontaneous breathing trial' named entity 'weaning'

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