About: Potential Neuroinvasive Pathways of SARS‐CoV‐2: Deciphering the Spectrum of Neurological Deficit Seen in Coronavirus Disease 2019 (COVID‐19)

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Potential Neuroinvasive Pathways of SARS‐CoV‐2: Deciphering the Spectrum of Neurological Deficit Seen in Coronavirus Disease 2019 (COVID‐19) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Potential Neuroinvasive Pathways of SARS‐CoV‐2: Deciphering the Spectrum of Neurological Deficit Seen in Coronavirus Disease 2019 (COVID‐19)
Creator	Mannan Baig, Abdul Sanders, Erin
source	Medline; PMC
abstract	COVID‐19 was declared a global pandemic on March 11, 2020. Scientists and clinicians must acknowledge that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) has the potential to attack the human body in multiple ways simultaneously and exploit any weaknesses of its host. A multipronged attack could potentially explain the severity and extensive variety of signs and symptoms observed in patients with COVID‐19. Understanding the diverse tactics of this virus to infect the human body is both critical and incredibly complex. Although patients diagnosed with COVID‐19 have primarily presented with pulmonary involvement, viral invasion, and injury to diverse end organs is also prevalent and well documented in these patients, but has been largely unheeded. Human organs known for Angiotensin‐Converting Enzyme 2 (ACE2) expression including the gastrointestinal tract, kidneys, heart, adrenals, brain, and testicles are examples of extra‐pulmonary tissues with confirmed invasion by SARS‐CoV‐2. Initial multiple organ involvement may present with vague signs and symptoms to alert healthcare professionals early in the course of COVID‐19. Another example of an ongoing, yet neglected element of the syndromic features of COVID‐19, are the reported findings of loss of smell, altered taste, ataxia, headache, dizziness, and loss of consciousness, which suggest a potential for neural involvement. In this review, we further deliberate on the neuroinvasive potential of SARS‐CoV‐2, the neurologic symptomology observed in COVID‐19, the host‐virus interaction, possible routes of SARS‐CoV‐2 to invade the central nervous system (CNS), other neurologic considerations for patients with COVID‐19, and a collective call to action. This article is protected by copyright. All rights reserved.
has issue date	2020-06-03(xsd:dateTime)
bibo:doi	10.1002/jmv.26105
bibo:pmid	32492193
has license	no-cc
sha1sum (hex)	dec75f95aef9acb532d86be6093c59a59ef3eb41
schema:url	https://doi.org/10.1002/jmv.26105
resource representing a document's title	Potential Neuroinvasive Pathways of SARS‐CoV‐2: Deciphering the Spectrum of Neurological Deficit Seen in Coronavirus Disease 2019 (COVID‐19)
has PubMed Central identifier	PMC7300748
has PubMed identifier	32492193
schema:publication	J Med Virol
resource representing a document's body	covid:dec75f95aef9acb532d86be6093c59a59ef3eb41#body_text
is schema:about of	named entity 'Neurological' named entity 'Coronavirus' named entity 'COVID-19' named entity 'MRI' named entity 'influenza' named entity 'neuroinvasive' named entity 'Italy' named entity 'SARS-CoV-1' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'subarachnoid space' named entity 'SARS-CoV-2' named entity 'histopathology' named entity 'Acute respiratory failure' named entity 'electroencephalogram' named entity 'Forensic Medicine' named entity 'biventricular' named entity 'Italy' named entity 'virus' named entity 'neurodegenerative diseases' named entity 'pathogen' named entity 'neurons' named entity 'COVID19' named entity 'cytopathic effects' named entity 'Miller Fisher syndrome' named entity 'autopsy report' named entity 'morbidity' named entity 'anticoagulation' named entity 'tissue damage' named entity 'blood vessels' named entity 'meninges' named entity 'infection' named entity 'Hebei Medical University' named entity 'infection' named entity 'COVID-19 outbreak' named entity 'virus' named entity 'neurologic' named entity 'nasal swab' named entity 'hematogenous' named entity 'virion' named entity 'RT-PCR' named entity 'COVID-19' named entity 'BBB' named entity 'SARS-CoV-2' named entity 'AMS' named entity 'SARS-CoV-2' named entity 'China' named entity 'virus' named entity 'SARS-CoV-2' named entity 'skull' named entity 'COVID19' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'glia' named entity 'gyrus rectus' named entity 'peripheral nerves' named entity 'organ' named entity 'MRI' named entity 'case report' named entity 'conjunctivitis' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'poliovirus' named entity 'epithelial' named entity 'China' named entity 'olfactory' named entity 'SARS-CoV-2' named entity 'herpesviruses' named entity 'immune-privileged' named entity 'COVID' named entity 'virus' named entity 'ACE2' named entity 'tetraparesis' named entity 'meningoencephalitis' named entity 'brainstem' named entity 'SARS-CoV-2' named entity 'RT-PCR' named entity 'stroke' named entity 'BBB' named entity 'ethmoid bone'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software