About: Prospects for the creation of new antiviral drugs based on glycyrrhizic acid and its derivatives (a review)

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Prospects for the creation of new antiviral drugs based on glycyrrhizic acid and its derivatives (a review)
Creator	Tolstikov, G Baltina, L Kondratenko, R Plyasunova, O Pokrovskii, A
Source	Medline; PMC
abstract	The review is devoted to the problem of creating new antiviral drugs based on glycyrrhizic acid (GA), the major triterpene glycoside extracted from roots of common and Ural licorice (Glycyrrhiza glabra L. and G. uralensis Fisher, respectively). Published data on the natural GA sources, antiviral activity of GA and its derivatives, clinical applications of GA-based drugs, and the properties of GA-containing biologically active nutrient additives are summarized. Possible mechanisms of the antiviral activity of GA and its derivatives are examined. It is shown that chemical modification of GA is a promising way of designing new highly active antiviral drugs for the prophylaxis and treatment of HIV, hepatitis B and C, corona-virus, and herpes simplex virus infections.
has issue date	2010-02-04(xsd:dateTime)
bibo:doi	10.1007/s11094-010-0348-2
bibo:pmid	32214533
has license	no-cc
sha1sum (hex)	df54b21db0cc3854ff4f1fd272de543afdcfb6b1
schema:url	https://doi.org/10.1007/s11094-010-0348-2
resource representing a document's title	Prospects for the creation of new antiviral drugs based on glycyrrhizic acid and its derivatives (a review)
has PubMed Central identifier	PMC7089237
has PubMed identifier	32214533
schema:publication	Pharm Chem J
resource representing a document's body	covid:df54b21db0cc3854ff4f1fd272de543afdcfb6b1#body_text
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