About: Lactate Dehydrogenase-Elevating Virus, Equine Arteritis Virus, and Simian Hemorrhagic Fever Virus: A New Group of Positive-Strand RNA Viruses

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About: Lactate Dehydrogenase-Elevating Virus, Equine Arteritis Virus, and Simian Hemorrhagic Fever Virus: A New Group of Positive-Strand RNA Viruses Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Lactate Dehydrogenase-Elevating Virus, Equine Arteritis Virus, and Simian Hemorrhagic Fever Virus: A New Group of Positive-Strand RNA Viruses
Creator	Moennigt, Volker Plagemann', Peter
source	Elsevier; Medline; PMC
abstract	Publisher Summary The last comprehensive reviews of nonarbotogaviruses included discussions on pestiviruses, rubella virus, lactate dehydrogenase-elevating virus (LDV), equine arteritis virus (EAV), simian hemorrhagic fever virus (SHFV), cell fusion agent, and nonarboflaviviruses. The inclusion of all these viruses in the family Togaviridae was largely based on the similarities in morphological and physical–chemical properties of these viruses, and in the sizes and polarities of their genomes. In the intervening years, considerable new information on the replication strategies of these viruses and the structure and organization of their genomes has become available that has led to the reclassification or suggestions for reclassification of some of them. The replication strategy of EAV resembles that of the coronaviruses, involving a 3'-coterminal nested set of mRNAs. Therefore, EAV has been suggested to be included in a virus superfamily, along with coronaviruses and toroviruses. Recent evidence indicates that LDV not only resembles EAV in morphology, virion and genome size, and number and size of their structural proteins, but also in genome organization and replication via a 3'-coterminal set of mRNAs. SHFV, although not fully characterized, exhibits properties resembling those of LDV and EAV, and the recent evidence suggest that it may possess the same genome organization as these viruses. The three viruses may, therefore, represent a new family of positive-strand RNA viruses and are reviewed together in this chapter. In this chapter, emphasis is on the recent information concerning their molecular properties and pathogenesis in vitro and in vivo and on the host immune responses to infections by these viruses.
has issue date	1992-12-31(xsd:dateTime)
bibo:doi	10.1016/s0065-3527(08)60036-6
bibo:pmid	1315480
has license	els-covid
sha1sum (hex)	e19e91291e9436e0fe28a304a7f0a258cb6cee2d
schema:url	https://doi.org/10.1016/s0065-3527%2808%2960036-6
resource representing a document's title	Lactate Dehydrogenase-Elevating Virus, Equine Arteritis Virus, and Simian Hemorrhagic Fever Virus: A New Group of Positive-Strand RNA Viruses
has PubMed Central identifier	PMC7131515
has PubMed identifier	1315480
schema:publication	Advances in Virus Research
resource representing a document's body	covid:e19e91291e9436e0fe28a304a7f0a258cb6cee2d#body_text
is schema:about of	named entity 'LACTATE' named entity 'ELEVATING' named entity 'STRAND' named entity 'RNA VIRUSES' named entity 'VIRUS' named entity 'SIMIAN HEMORRHAGIC FEVER VIRUS' named entity 'POSITIVE' named entity 'GROUP' named entity 'NEW' named entity 'SIMIAN HEMORRHAGIC FEVER VIRUS' named entity 'starch' named entity 'virus' named entity 'spinal cord' named entity 'EAV' named entity 'motor neurons' named entity 'lymphocytes' named entity 'infection' named entity 'infection' named entity 'hemorrhagic disease' named entity 'United States' named entity 'viruses' named entity 'saliva' named entity 'transcription' named entity 'glycoprotein' named entity 'young mice' named entity 'immunogenic' named entity 'neurovirulence' named entity 'molecular biology' named entity 'African monkeys' named entity 'nucleocapsid protein' named entity 'Plasma' named entity 'macrophages' named entity 'antibodies' named entity 'Infection' named entity 'motor neuron' named entity 'coronaviruses' named entity 'immunogenicity' named entity 'antigen' named entity 'RNAs' named entity 'genetic linkage' named entity 'research model' named entity 'protein' named entity 'RNA' named entity 'equine' named entity 'EAV' named entity 'critical role' named entity 'togaviruses' named entity 'polyclonal' named entity 'motor neurons' named entity 'corticosterone' named entity 'Miami' named entity 'dose effect' named entity 'ecotropic' named entity 'protein' named entity 'isotypes' named entity 'EAV' named entity 'IDH' named entity 'coronaviruses' named entity 'electron microscopy' named entity 'MAb' named entity 'LDH' named entity 'infection' named entity 'motor neurons' named entity 'rat' named entity 'antibody' named entity 'macaque monkey' named entity 'Macaca fascicularis' named entity 'Arteriviridae' named entity 'RNAs' named entity 'ORFs' named entity 'hemorrhagic fever' named entity 'virus' named entity 'interferon' named entity 'staining' named entity 'virulence' named entity 'patas monkey' named entity 'glycerol' named entity 'virulence properties' named entity 'peritoneum' named entity 'coronaviruses'

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