About: Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014

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About: Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014
Creator	Schweiger, Brunhilde Biere, Barbara Fritsch, Annemarie
Source	PMC
abstract	INTRODUCTION: Recent data on influenza C virus indicate a possible higher clinical impact in specified patient populations than previously thought. AIM: We aimed to investigate influenza C virus circulation in Germany. METHODS: A total of 1,588 samples from 0 to 4 year-old children presenting as outpatients with influenza-like illness (ILI) or acute respiratory infection were analysed retrospectively. The samples represented a subset of all samples from the German national surveillance system for influenza in this age group in 2012–14. The presence of influenza C virus was investigated by real-time PCR. For positive samples, information on symptoms as well as other respiratory virus co-infections was considered. Retrieved influenza C viral sequences were phylogenetically characterised. RESULTS: Influenza C viral RNA was detected in 20 (1.3% of) samples, including 16 during the 2012/13 season. The majority (18/20) of influenza C-positive patients had ILI according to the European Union definition, one patient had pneumonia. Viruses belonged to the C/Sao Paulo and C/Kanagawa lineages. Most (11/20) samples were co-infected with other respiratory viruses. CONCLUSION: Our data are the first on influenza C virus circulation in Germany and notably from a European national surveillance system. The low detection frequency and the identified virus variants confirm earlier observations outside a surveillance system. More virus detections during the 2012/13 season indicate a variable circulation intensity in the different years studied. Influenza C virus can be considered for ILI patients. Future studies addressing its clinical impact, especially in patients with severe disease are needed.
has issue date	2019-03-07(xsd:dateTime)
bibo:doi	10.2807/1560-7917.es.2019.24.10.1800174
bibo:pmid	30862333
has license	cc-by
sha1sum (hex)	e1f6b17bdd06ae44978e5359fbe7df68ac5fa1cf
schema:url	https://doi.org/10.2807/1560-7917.es.2019.24.10.1800174
resource representing a document's title	Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014
has PubMed Central identifier	PMC6415498
has PubMed identifier	30862333
schema:publication	Euro Surveill
resource representing a document's body	covid:e1f6b17bdd06ae44978e5359fbe7df68ac5fa1cf#body_text
is schema:about of	named entity 'RETROSPECTIVE ANALYSIS' named entity 'INFLUENZA C VIRUS' named entity 'DATA' named entity 'INFLUENZA SURVEILLANCE' named entity 'SCHOOL CHILDREN' named entity 'SURVEILLANCE SYSTEM' named entity 'RESPIRATORY INFECTIONS' named entity 'GERMANY' named entity 'NATIONAL' named entity 'PRE-SCHOOL' named entity 'Germany' named entity 'ARI' named entity 'Sao Paulo' named entity 'pathogen' named entity 'Catalonia' named entity 'influenza' named entity 'virus species' named entity 'Bronchitis' named entity 'influenza' named entity 'fever' named entity 'France' named entity 'phylogenetic' named entity 'esterase' named entity 'Japan' named entity 'influenza' named entity 'virus' named entity 'influenza C virus' named entity 'body temperature' named entity 'influenza' named entity 'detection limit' named entity 'influenza C virus' named entity 'Germany' named entity 'qPCR' named entity '3.5' named entity 'Peru' named entity 'clinical presentation' named entity 'influenza' named entity 'haemagglutinin' named entity 'virus' named entity 'virus' named entity 'homology' named entity 'amplicon' named entity 'Kanagawa' named entity 'influenza' named entity 'Germany' named entity 'viruses' named entity 'genome' named entity 'cough' named entity 'Polymerase' named entity 'co-infected' named entity 'respiratory symptoms' named entity 'virus' named entity 'RNA' named entity 'Europe' named entity 'influenza C virus' named entity 'influenza virus' named entity 'Spain' named entity 'Canada' named entity 'GE Healthcare' named entity 'muscular pain' named entity 'virus' named entity 'influenza' named entity 'PCR' named entity 'Philippines' named entity 'evolution' named entity 'infection' named entity 'internal control' named entity '4/9' named entity 'synthetic double stranded DNA' named entity 'viruses' named entity 'HRV' named entity 'virus' named entity 'France' named entity 'amplicon' named entity 'influenza' named entity 'gene' named entity 'Reverse Transcriptase' named entity 'virus' named entity 'cross-reactivity'

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